A review of aptamer-based SERS biosensors: Design strategies and applications
文献类型：期刊论文
| 作者 | Muhammad, Muhammad1,2; Huang, Qing1,2
|
| 刊名 | TALANTA
 |
| 出版日期 | 2021-05-15 |
| 卷号 | 227 |
| ISSN号 | 0039-9140 |
| 关键词 | Surface-enhanced Raman spectroscopy (SERS) Aptamers Nanoparticles (NPs) Nanostructure Biosensors |
| DOI | 10.1016/j.talanta.2021.122188 |
| 通讯作者 | Huang, Qing(huangq@ipp.ac.cn) |
| 英文摘要 | Surface-enhanced Raman spectroscopy, due to its high sensitivity, unique vibrational fingerprint identification of molecules and easy operation, has been extensively applied in different fields. Aptamers, being the unique single stranded DNA/RNA sequences that can specifically recognize and seize the target analytes, combined with Surface-enhanced Raman spectroscopy (SERS), can offer potent multiplex detection capacity with high specificity and sensitivity. In this review, we summarize and classify the general working strategies of different types of aptamer-based SERS biosensors with diversified protocols which either take aptamer conformational change as intrinsic reporter, or make use of various extrinsic Raman reporters in different sensor designs via on/off approach, sandwich-type and magnetic nanoparticles (NPs)-assisted approach, and catalytic reaction assisted approach with amplification of alternative Raman signals. The advantages, applications and perspectives of these aptamer-based SERS biosensors are also discussed. |
| WOS关键词 | ENHANCED RAMAN-SCATTERING ; LABEL-FREE DETECTION ; CIRCULATING TUMOR DNA ; QUANTITATIVE-ANALYSIS ; ULTRASENSITIVE DETECTION ; AMPLIFICATION STRATEGY ; SENSITIVE DETECTION ; DETECTION PLATFORM ; SPECTROSCOPY ; RECOGNITION |
| 资助项目 | National Natural Science Foundation of China[11635013] ; China Scholarship Council of China government |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | ELSEVIER |
| WOS记录号 | WOS:000657099100002 |
| 资助机构 | National Natural Science Foundation of China ; China Scholarship Council of China government |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/123644]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Huang, Qing |
| 作者单位 | 1.Univ Sci & Technol China, Sci Isl Branch, Grad Sch, Beijing, Peoples R China 2.Chinese Acad Sci, Inst Intelligent Machines, Hefei Inst Phys Sci, CAS Key Lab High Magnet Field & Ion Beam Phys Bio, Hefei 230031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Muhammad, Muhammad,Huang, Qing. A review of aptamer-based SERS biosensors: Design strategies and applications[J]. TALANTA,2021,227. |
| APA | Muhammad, Muhammad,&Huang, Qing.(2021).A review of aptamer-based SERS biosensors: Design strategies and applications.TALANTA,227. |
| MLA | Muhammad, Muhammad,et al."A review of aptamer-based SERS biosensors: Design strategies and applications".TALANTA 227(2021). |
入库方式： OAI收割
来源：合肥物质科学研究院
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