The prognostic significance of serum gamma-glutamyltransferase levels and AST
文献类型:期刊论文
作者 | Li-xiang Zhang1; Yang Lv2; A-Man Xu1; Huan-zhong Wang3![]() |
刊名 | BMC Cancer
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出版日期 | 2019 |
卷号 | 19 |
ISSN号 | 1471-2407 |
其他题名 | The prognostic significance of serum gamma-glutamyltransferase levels and AST |
英文摘要 | Background Blood counting and the liver function tests, as the routine examinations, can reflect the immune and nutritional status of the body, our aim is to assess the prognostic significance of serum gamma-glutamyltransferase (GGT) levels and AST Methods Clinico-pathological data of 414 patients with primary hepatic carcinoma in the 1st Affiliated Hospital of Anhui Medical College between January 2007 to January 2014 was analyzed retrospectively in this study. Survival curves were described by Kaplan-Meier method and compared by Log-rank test, univariate and multivariate analysis were used to identify the prognostic factors. Results GGT was positively correlated with the tumor size( P ?=?0.000), tumor volume ( P ?=?0.000), tumor volume percent ( P ?=?0.004), TNM stage( P ?=?0.009), 1-year survival rate ( P ?=?0.000), 3- years survival rate ( P ?=?0.000) and 5-years survival rate( P ?=?0.000). The serum ALT P ?=?0.047), tumor size( P ?=?0.002), tumor volume ( P ?=?0.010), tumor volume percent ( P ?=?0.005), TNM stage( P ?=?0.006), liver cirrhosis( P ?=?0.003), 3- years survival rate ( P ?=?0.032) and 5-years survival rate( P ?=?0.000). The Kaplan-Meier curves showed that the patients with primary hepatic carcinoma had a longer time in the low GGT group and low AST P ?0.05). The univariate and multivariate analyses showed that TNM stage, differentiation grade, tumor volume, GGT and AST Conclusions GGT and AST |
语种 | 英语 |
源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/124143] ![]() |
专题 | 中国科学院合肥物质科学研究院 |
作者单位 | 1.安徽医科大学 2.Second People’s Hospital of Jingmen City 3.Hefei Institutes of Physical Science, Chinese Academy of Sciences |
推荐引用方式 GB/T 7714 | Li-xiang Zhang,Yang Lv,A-Man Xu,et al. The prognostic significance of serum gamma-glutamyltransferase levels and AST[J]. BMC Cancer,2019,19. |
APA | Li-xiang Zhang,Yang Lv,A-Man Xu,&Huan-zhong Wang.(2019).The prognostic significance of serum gamma-glutamyltransferase levels and AST.BMC Cancer,19. |
MLA | Li-xiang Zhang,et al."The prognostic significance of serum gamma-glutamyltransferase levels and AST".BMC Cancer 19(2019). |
入库方式: OAI收割
来源:合肥物质科学研究院
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