Expression profile of a novel glutathione S-transferase gene in the marine polychaete Perinereis aibuhitensis in short-term responses to phenanthrene, fluoranthene, and benzo[alpha]pyrene
文献类型：期刊论文
| 作者 | Yuan, Xiutang2,3 ; Zhao, Huan1; Wang, Yinan1,2; Wang, Lili2; Li, Dongmei2; Zhang, Anguo2; Yang, Xiaolong2; Ma, Xindong2; Yang, Dazuo1; Zhou, Yibing1
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| 刊名 | MARINE POLLUTION BULLETIN
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| 出版日期 | 2021-08-01 |
| 卷号 | 169页码:6 |
| 关键词 | Polychaete PAH biotransformation GST Liaohe Estuary |
| ISSN号 | 0025-326X |
| DOI | 10.1016/j.marpolbul.2021.112552 |
| 通讯作者 | Yuan, Xiutang(xtyuan@yic.ac.cn) |
| 英文摘要 | Polychaete worms can eliminate polycyclic aromatic hydrocarbons (PAHs) in environments through a mechanism that increases their water solubility. This detoxification starts with cytochrome P450 enzymes (CYPs) and then with glutathione S-transferases (GSTs). Here, a novel GST gene was identified and characterized from the widespread polychaete Perinereis aibuhitensis. The full-length cDNA of GST is 1544 bp and encodes 256 amino acids, belonging to the omega class. Gene expression patterns in P. aibuhitensis showed that its transcriptional level was positively correlated with the concentration of benzo[alpha]pyrene (0.5, 2, 4, and 8 mu g/L) exposure but was negatively correlated with a PAH benzene ring after it was exposed to the same mass concentrations of fluoranthene (3.2 mu g/L), phenanthrene (2.9 mu g/L), and benzo[alpha]pyrene (4.0 mu g/L) during the 14-day experimentation. These findings indicate that omega GST may play an important role in the phase II detoxification of PAHs in polychaete worms, and the persistence and bioavailability of PAHs may depend on benzene rings. |
| WOS关键词 | POLYCYCLIC AROMATIC-HYDROCARBONS ; MOLECULAR-CLONING ; PAHS ; METABOLITES ; SEDIMENT ; ESTUARY ; NUNTIA |
| 资助项目 | National Natural Science Foundation of China[41106115] ; National Natural Science Foundation of China[41306138] ; National Marine Public Welfare Research Project[201305043] |
| WOS研究方向 | Environmental Sciences & Ecology ; Marine & Freshwater Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:000679313100012 |
| 资助机构 | National Natural Science Foundation of China ; National Marine Public Welfare Research Project |
| 源URL | [http://ir.yic.ac.cn/handle/133337/29545]  |
| 专题 | 海岸带生物学与生物资源利用重点实验室 烟台海岸带研究所_近岸生态与环境实验室 |
| 通讯作者 | Yuan, Xiutang |
| 作者单位 | 1.Dalian Ocean Univ, Dalian 116023, Peoples R China 2.Minist Ecol & Environm, Natl Marine Environm Monitoring Ctr, Dalian 116023, Peoples R China 3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yuan, Xiutang,Zhao, Huan,Wang, Yinan,et al. Expression profile of a novel glutathione S-transferase gene in the marine polychaete Perinereis aibuhitensis in short-term responses to phenanthrene, fluoranthene, and benzo[alpha]pyrene[J]. MARINE POLLUTION BULLETIN,2021,169:6. |
| APA | Yuan, Xiutang.,Zhao, Huan.,Wang, Yinan.,Wang, Lili.,Li, Dongmei.,...&Zhou, Yibing.(2021).Expression profile of a novel glutathione S-transferase gene in the marine polychaete Perinereis aibuhitensis in short-term responses to phenanthrene, fluoranthene, and benzo[alpha]pyrene.MARINE POLLUTION BULLETIN,169,6. |
| MLA | Yuan, Xiutang,et al."Expression profile of a novel glutathione S-transferase gene in the marine polychaete Perinereis aibuhitensis in short-term responses to phenanthrene, fluoranthene, and benzo[alpha]pyrene".MARINE POLLUTION BULLETIN 169(2021):6. |
入库方式： OAI收割
来源：烟台海岸带研究所
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