Three Polymers from the Sea: Unique Structures, Directional Modifications, and Medical Applications
文献类型：期刊论文
| 作者 | Wang, Lei ; Li, Wenjun; Qin, Song
|
| 刊名 | POLYMERS
 |
| 出版日期 | 2021-08-01 |
| 卷号 | 13期号:15页码:18 |
| 关键词 | alginate chitosan collagen biomaterials tissue engineering |
| DOI | 10.3390/polym13152482 |
| 通讯作者 | Qin, Song(sqin@yic.ac.cn) |
| 英文摘要 | With the increase of wounds and body damage, the clinical demand for antibacterial, hemostatic, and repairable biomaterials is increasing. Various types of biomedical materials have become research hotspots. Of these, and among materials derived from marine organisms, the research and application of alginate, chitosan, and collagen are the most common. Chitosan is mainly used as a hemostatic material in clinical applications, but due to problems such as the poor mechanical strength of a single component, the general antibacterial ability, and fast degradation speed research into the extraction process and modification mainly focuses on the improvement of the above-mentioned ability. Similarly, the research and modification of sodium alginate, used as a material for hemostasis and the repair of wounds, is mainly focused on the improvement of cell adhesion, hydrophilicity, degradation speed, mechanical properties, etc.; therefore, there are fewer marine biological collagen products. The research mainly focuses on immunogenicity removal and mechanical performance improvement. This article summarizes the source, molecular structure, and characteristics of alginate, chitosan, and collagen from marine organisms; and introduces the biological safety, clinical efficacy, and mechanism of action of these materials, as well as their extraction processes and material properties. Their modification and other issues are also discussed, and their potential clinical applications are examined. |
| WOS关键词 | MORPHOGENETIC PROTEIN-2 DELIVERY ; OXIDIZED ALGINATE ; SODIUM ALGINATE ; ARTIFICIAL CORNEA ; COLLAGEN SPONGE ; CARBON-DIOXIDE ; FISH COLLAGEN ; STEM-CELLS ; CHITOSAN ; BONE |
| 资助项目 | Department of Science and Technology of Shandong Province[2019JZZY011103] |
| WOS研究方向 | Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000682171400001 |
| 资助机构 | Department of Science and Technology of Shandong Province |
| 源URL | [http://ir.yic.ac.cn/handle/133337/29624]  |
| 专题 | 烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室 |
| 通讯作者 | Qin, Song |
| 作者单位 | Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Biol & Bioresource Utilizat, Yantai 264003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Lei,Li, Wenjun,Qin, Song. Three Polymers from the Sea: Unique Structures, Directional Modifications, and Medical Applications[J]. POLYMERS,2021,13(15):18. |
| APA | Wang, Lei,Li, Wenjun,&Qin, Song.(2021).Three Polymers from the Sea: Unique Structures, Directional Modifications, and Medical Applications.POLYMERS,13(15),18. |
| MLA | Wang, Lei,et al."Three Polymers from the Sea: Unique Structures, Directional Modifications, and Medical Applications".POLYMERS 13.15(2021):18. |
入库方式： OAI收割
来源：烟台海岸带研究所
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