Broadband Terahertz Spectroscopy of Glutathione
文献类型：期刊论文
| 作者 | Guo, G; Zhu, ZJ; Shen, JX; Zhang, ZC; Zhang, JB; Zhao, DM; Zhao, HW |
| 刊名 | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2020 |
| 卷号 | 48期号:10页码:1367-1374 |
| 关键词 | TIME-DOMAIN SPECTROSCOPY CRYSTAL-STRUCTURE DIELECTRIC-SPECTROSCOPY INFRARED-SPECTROSCOPY GAS-PHASE DYNAMICS FORM PROTEINS SPECTRA |
| ISSN号 | 0253-3820 |
| DOI | 10.19756/j.issn.0253-3820.201148 |
| 文献子类 | 期刊论文 |
| 英文摘要 | The conformation of glutathione is of great significance for its biological function. In this study , the absorption spectra of reduced (GSH) and oxidized (GSSG) glutathione in the frequency range of 0. 5-12 THz were obtained by the air plasma terahertz time-domain spectroscopy (THz-TDS ) . The results demonstrated that GSH had rich characteristic absorption peaks in the THz region, while GSSG presented a monotonous absorption spectrum without obvious peaks. Combined with powder X-ray diffraction (PXRD) , GSH had a certain crystal structure and GSSG was amorphous, suggesting that the THz spectroscopy was sensitive to the molecular structure and crystal form. The density functional theory (DFT) calculation based on the GSH crystal structure was performed to simulate the THz absorption spectrum and analyze the vibrational property. The result showed that GSH molecule could form rich intra-and inter-molecular hydrogen bonds, which helped to constrain flexible peptide. Lattice vibration and hydrogen bonding of GSH can effectively resonate with THz waves. The different THz absorption peaks of GSH correspond to different collective or local molecular vibrations which were closely related to the hydrogen bonding interactions. The study may help to deepen the understanding of GSH molecular conformation and weak interactions. |
| 语种 | 中文 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/32736]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China 2.Zhejiang Univ Technol, Coll Chem Engn, Hangzhou 310014, Peoples R China 3.Chinese Acad Sci, Shanghai Adv Res Inst, Zhangjiang Lab, Shanghai 201210, Peoples R China |
| 推荐引用方式 GB/T 7714 | Guo, G,Zhu, ZJ,Shen, JX,et al. Broadband Terahertz Spectroscopy of Glutathione[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2020,48(10):1367-1374. |
| APA | Guo, G.,Zhu, ZJ.,Shen, JX.,Zhang, ZC.,Zhang, JB.,...&Zhao, HW.(2020).Broadband Terahertz Spectroscopy of Glutathione.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,48(10),1367-1374. |
| MLA | Guo, G,et al."Broadband Terahertz Spectroscopy of Glutathione".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 48.10(2020):1367-1374. |
入库方式： OAI收割
来源：上海应用物理研究所
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