Meta-DNA structures
文献类型：期刊论文
| 作者 | Yao, GB; Zhang, F; Wang, F; Peng, TH; Liu, H; Poppleton, E; Sulc, P; Jiang, SX; Liu, L; Gong, C |
| 刊名 | NATURE CHEMISTRY
 |
| 出版日期 | 2020 |
| 卷号 | 12期号:11页码:1067-+ |
| ISSN号 | 1755-4330 |
| 关键词 | COMPUTATION NANOROBOT SHAPES TILES |
| DOI | 10.1038/s41557-020-0539-8 |
| 文献子类 | 期刊论文 |
| 英文摘要 | DNA origami has emerged as a highly programmable method to construct customized objects and functional devices in the 10-100 nm scale. Scaling up the size of the DNA origami would enable many potential applications, which include metamaterial construction and surface-based biophysical assays. Here we demonstrate that a six-helix bundle DNA origami nanostructure in the submicrometre scale (meta-DNA) could be used as a magnified analogue of single-stranded DNA, and that two meta-DNAs that contain complementary 'meta-base pairs' can form double helices with programmed handedness and helical pitches. By mimicking the molecular behaviours of DNA strands and their assembly strategies, we used meta-DNA building blocks to form diverse and complex structures on the micrometre scale. Using meta-DNA building blocks, we constructed a series of DNA architectures on a submicrometre-to-micrometre scale, which include meta-multi-arm junctions, three-dimensional (3D) polyhedrons, and various 2D/3D lattices. We also demonstrated a hierarchical strand-displacement reaction on meta-DNA to transfer the dynamic features of DNA into the meta-DNA. This meta-DNA self-assembly concept may transform the microscopic world of structural DNA nanotechnology. |
| 语种 | 英语 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/33003]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 作者单位 | 1.Rutgers State Univ, Dept Chem, Newark, NJ USA 2.Chinese Acad Sci, Shanghai Inst Appl Phys, CAS Key Lab Interfacial Phys & Technol, Div Phys Biol, Shanghai, Peoples R China 3.Shanghai Jiao Tong Univ, Sch Med, Shanghai Key Lab Nucle Acids Chem & Nanomed, Inst Mol Med,Renji Hosp, Shanghai, Peoples R China 4.East China Normal Univ, Sch Chem & Mol Engn, Shanghai Key Lab Green Chem & Chem Proc, Shanghai, Peoples R China 5.Chinese Acad Sci, Shanghai Adv Res Inst, Zhangjiang Lab, Bioimaging Ctr,Shanghai Synchrotron Radiat Facil, Shanghai, Peoples R China 6.Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, Frontiers Sci Ctr Transformat Mol, Shanghai, Peoples R China 7.Shanghai Jiao Tong Univ, Natl Ctr Translat Med, Shanghai, Peoples R China 8.Arizona State Univ, Sch Mol Sci, Tempe, AZ 85287 USA 9.Arizona State Univ, Ctr Mol Design & Biomimet, Biodesign Inst, Tempe, AZ 85287 USA 10.Southern Med Univ, Affiliated Fengxian Hosp, Shanghai Jiao Tong Univ Affiliated Peoples Hosp 6, Joint Res Ctr Precis Med, South Campus, Shanghai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yao, GB,Zhang, F,Wang, F,et al. Meta-DNA structures[J]. NATURE CHEMISTRY,2020,12(11):1067-+. |
| APA | Yao, GB.,Zhang, F.,Wang, F.,Peng, TH.,Liu, H.,...&Yan, H.(2020).Meta-DNA structures.NATURE CHEMISTRY,12(11),1067-+. |
| MLA | Yao, GB,et al."Meta-DNA structures".NATURE CHEMISTRY 12.11(2020):1067-+. |
入库方式： OAI收割
来源：上海应用物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。