Metal-free electrochemical synthesis of alpha-ketoamides via decarboxylative coupling of alpha-keto acids with isocyanides and water
文献类型：期刊论文
| 作者 | Zhao, Feng; Meng, Na; Sun, Ting; Wen, Jiangwei; Zhao, Xiaohui; Wei, Wei |
| 刊名 | ORGANIC CHEMISTRY FRONTIERS
 |
| 出版日期 | 2021 |
| 英文摘要 | A mild and environmentally benign electrochemical strategy has been developed for the synthesis of alpha-ketoamides via a decarboxylative coupling reaction of alpha-keto acids with isocyanides and water. The present reaction was efficiently conducted under constant current electrolysis using n-Bu4NI as the electrolyte in an undivided cell. A series of alpha-ketoamides could be conveniently and rapidly constructed at room temperature in the absence of transition metal catalysts and external oxidants. Mechanistic studies suggested that water not only served as a starting material to construct alpha-ketoamides, but also played an important role in promoting the electrochemical redox of alpha-keto acids. |
| 源URL | [http://210.75.249.4/handle/363003/60688]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Zhao, Feng,Meng, Na,Sun, Ting,et al. Metal-free electrochemical synthesis of alpha-ketoamides via decarboxylative coupling of alpha-keto acids with isocyanides and water[J]. ORGANIC CHEMISTRY FRONTIERS,2021. |
| APA | Zhao, Feng,Meng, Na,Sun, Ting,Wen, Jiangwei,Zhao, Xiaohui,&Wei, Wei.(2021).Metal-free electrochemical synthesis of alpha-ketoamides via decarboxylative coupling of alpha-keto acids with isocyanides and water.ORGANIC CHEMISTRY FRONTIERS. |
| MLA | Zhao, Feng,et al."Metal-free electrochemical synthesis of alpha-ketoamides via decarboxylative coupling of alpha-keto acids with isocyanides and water".ORGANIC CHEMISTRY FRONTIERS (2021). |
入库方式： OAI收割
来源：西北高原生物研究所
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