Separation of a new triterpenoid saponin together with six known ones from Clematis tangutica (Maxim.) Korsh and evaluation of their cytotoxic activities
文献类型：期刊论文
| 作者 | Wei, Yangfei; Chen, Tao; Wang, Shuo; Shen, Cheng; Yan, Shuping ; Song, Zhibo; Liu, Yarong; Yang, Fengmei; Hai, Ping; Li, Yulin
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| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 出版日期 | 2021 |
| 关键词 | Clematis tangutica (Maxim ) Korsh triterpenoid saponins new compound high-speed counter-current chromatography cytotoxic activities |
| 英文摘要 | A new triterpenoid saponin, 3-O-beta-D-allopyranosyl (1 -> 3)-alpha-L-rhamnopyranosyl (1 -> 2)-alpha-L-arabinopyranosyl hederagenin 28-O-alpha-L-rhamnopyranosyl (1 -> 4)-beta-D-glucopyranosyl (1 -> 6)-beta-D-glucopyranosyl ester (IV), together with six known ones Hederacholichiside F (I), Tanguticoside B (II), Tauroside St-H-1 (III), Hederoside H-1 (V), Kalopanaxsaponin G (VI), Hederasaponin B (VII) were separated from Clematis tangutica (Maxim.) Korsh. Their cytotoxic activities were evaluated. Saponins IV (new compound) and I showed selective inhibitory activities against HGC-27 with IC50 values of 20.17 and 66.18 mu M. Saponin VII exhibited extensive inhibitory action against HGC-27, Hela and SK-OV-3 with IC50 values of 16.47-71.36 mu M. Saponin III showed selective inhibitory activity against SK-OV-3 with the IC50 value of 48.70 mu M. All isolated saponins were inactive (IC50 >150 mu M) to GES-1. |
| 源URL | [http://210.75.249.4/handle/363003/60711]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Wei, Yangfei,Chen, Tao,Wang, Shuo,et al. Separation of a new triterpenoid saponin together with six known ones from Clematis tangutica (Maxim.) Korsh and evaluation of their cytotoxic activities[J]. NATURAL PRODUCT RESEARCH,2021. |
| APA | Wei, Yangfei.,Chen, Tao.,Wang, Shuo.,Shen, Cheng.,Yan, Shuping.,...&Li, Yulin.(2021).Separation of a new triterpenoid saponin together with six known ones from Clematis tangutica (Maxim.) Korsh and evaluation of their cytotoxic activities.NATURAL PRODUCT RESEARCH. |
| MLA | Wei, Yangfei,et al."Separation of a new triterpenoid saponin together with six known ones from Clematis tangutica (Maxim.) Korsh and evaluation of their cytotoxic activities".NATURAL PRODUCT RESEARCH (2021). |
入库方式： OAI收割
来源：西北高原生物研究所
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