Fluorescent DNA-templated silver nanoclusters for highly sensitive detection of D-penicillamine
文献类型：期刊论文
| 作者 | Liu, Lingyuan; Zhang, Qianyi; Li, Feng; Wang, Mei; Sun, Jing ; Zhu, Shuyun
|
| 刊名 | SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
 |
| 出版日期 | 2021 |
| 卷号 | 253 |
| 关键词 | D-Penicillamine DNA-templated synthesis Silver nanoclusters Static quenching Fluorescence sensor |
| 英文摘要 | Herein, fluorescent DNA-templated silver nanoclusters (DNA-AgNCs) with red emission were synthesized and utilized as novel probe to detect D-penicillamine (D-Pen) for the first time. D-Pen molecules contain a thiol which can combine with Ag to form a non-fluorescent ground state complex, inducing the aggregation of DNA-AgNCs followed by the fluorescence quenching. The quenching mechanism is well-studied and found to be a static quenching process. This method can detect D-Pen in the range of 0.025-0.7 mu M with the detection limit as low as 8 nM, which is 1-3 orders of magnitude more sensitive than those based on other fluorescent nanoprobes. More importantly, the preparation procedure for DNA-AgNCs is fast and without the requirement of heavy metal ions. Thus, this detection strategy is time-saving and eco-friendly. Satisfactory recoveries have been acquired for monitoring D-Pen in human serum samples and pharmaceutical samples owing to the high sensitivity. (C) 2021 Elsevier B.V. All rights reserved. |
| 源URL | [http://210.75.249.4/handle/363003/60805]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Liu, Lingyuan,Zhang, Qianyi,Li, Feng,et al. Fluorescent DNA-templated silver nanoclusters for highly sensitive detection of D-penicillamine[J]. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,2021,253. |
| APA | Liu, Lingyuan,Zhang, Qianyi,Li, Feng,Wang, Mei,Sun, Jing,&Zhu, Shuyun.(2021).Fluorescent DNA-templated silver nanoclusters for highly sensitive detection of D-penicillamine.SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,253. |
| MLA | Liu, Lingyuan,et al."Fluorescent DNA-templated silver nanoclusters for highly sensitive detection of D-penicillamine".SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 253(2021). |
入库方式： OAI收割
来源：西北高原生物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。