Genomic Signature of Shifts in Selection and Alkaline Adaptation in Highland Fish
文献类型：期刊论文
| 作者 | Tong, Chao ; Li, Miao; Tang, Yongtao; Zhao, Kai
|
| 刊名 | GENOME BIOLOGY AND EVOLUTION
 |
| 出版日期 | 2021 |
| 卷号 | 13期号:5 |
| 关键词 | comparative genomics molecular evolution alkaline adaptation schizothoracine fish |
| 英文摘要 | Understanding how organisms adapt to aquatic life at high altitude is fundamental in evolutionary biology. This objective has been addressed primarily related to hypoxia adaptation by recent comparative studies, whereas highland fish has also long suffered extreme alkaline environment, insight into the genomic basis of alkaline adaptation has rarely been provided. Here, we compared the genomes or transcriptomes of 15 fish species, including two alkaline tolerant highland fish species and their six alkaline intolerant relatives, three alkaline tolerant lowland fish species, and four alkaline intolerant species. We found putatively consistent patterns of molecular evolution in alkaline tolerant species in a large number of shared orthologs within highland and lowland fish taxa. Remarkably, we identified consistent signatures of accelerated evolution and positive selection in a set of shared genes associated with ion transport, apoptosis, immune response, and energy metabolisms in alkaline tolerant species within both highland and lowland fish taxa. This is one of the first comparative studies that began to elucidate the consistent genomic signature of alkaline adaptation shared by highland and lowland fish. This finding also highlights the adaptive molecular evolution changes that support fish adapting to extreme environments at high altitude. |
| 源URL | [http://210.75.249.4/handle/363003/60811]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Tong, Chao,Li, Miao,Tang, Yongtao,et al. Genomic Signature of Shifts in Selection and Alkaline Adaptation in Highland Fish[J]. GENOME BIOLOGY AND EVOLUTION,2021,13(5). |
| APA | Tong, Chao,Li, Miao,Tang, Yongtao,&Zhao, Kai.(2021).Genomic Signature of Shifts in Selection and Alkaline Adaptation in Highland Fish.GENOME BIOLOGY AND EVOLUTION,13(5). |
| MLA | Tong, Chao,et al."Genomic Signature of Shifts in Selection and Alkaline Adaptation in Highland Fish".GENOME BIOLOGY AND EVOLUTION 13.5(2021). |
入库方式： OAI收割
来源：西北高原生物研究所
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