Ce4+-triggered cascade reaction for ratiometric fluorescence detection of alendronate
文献类型：期刊论文
| 作者 | Xia, Meng; Shi, Fengjin; Xia, Yinghui; Sun, Jing ; Zhao, Xian-En; Zhu, Shuyun
|
| 刊名 | SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
 |
| 出版日期 | 2021 |
| 卷号 | 251 |
| 关键词 | Ratiometric fluorescence sensor Cascade reaction Oxidase-mimics Ce4+ O-Phenlenediamine Ascorbic acid |
| 英文摘要 | A ratiometric fluorescence assay for alendronate (ALDS) has been designed with Ce4+-triggered cascade chromogenic reaction. This strategy involves three processes: (1) Ce4+ oxidizes ascorbic acid (AA) into dehydroascorbic acid (DHAA), which then condenses with o-phenlenediamine (OPD) to generate fluorescent 3(dihydroxyethyl)furo[3,4-b] quinoxaline-1-one (DFQ), presenting the maximum emission at 434 nm; (2) As oxidase-mimics, Ce4+ can oxidize OPD into fluorescent 2,3-diaminophenazine (DAP) which shows a strong emission at 568 nm; (3) ALDS inhibits the oxidation ability of Ce4+ towards OPD, thus inhibiting the generation of DAP. Accordingly, a homogeneous ratiometric fluorescence system with dual emission comes into being and the presence of ALDS can change the fluorescence intensity ratio obviously. With F434/F568 as readout, ALDS can be detected sensitively with the detection limit of 30 nM. Moreover, this ratiometric method was used to analyze ALDS in both human serum and pharmaceutical samples. (c) 2021 Elsevier B.V. All rights reserved. |
| 源URL | [http://210.75.249.4/handle/363003/60818]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Xia, Meng,Shi, Fengjin,Xia, Yinghui,et al. Ce4+-triggered cascade reaction for ratiometric fluorescence detection of alendronate[J]. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,2021,251. |
| APA | Xia, Meng,Shi, Fengjin,Xia, Yinghui,Sun, Jing,Zhao, Xian-En,&Zhu, Shuyun.(2021).Ce4+-triggered cascade reaction for ratiometric fluorescence detection of alendronate.SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,251. |
| MLA | Xia, Meng,et al."Ce4+-triggered cascade reaction for ratiometric fluorescence detection of alendronate".SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 251(2021). |
入库方式： OAI收割
来源：西北高原生物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。