Domestication Shapes the Community Structure and Functional Metagenomic Content of the Yak Fecal Microbiota
文献类型：期刊论文
| 作者 | Fu, Haibo; Zhang, Liangzhi; Fan, Chao; Liu, Chuanfa; Li, Wenjing ; Li, Jiye; Zhao, Xinquan; Jia, Shangang; Zhang, Yanming
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| 刊名 | FRONTIERS IN MICROBIOLOGY
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| 出版日期 | 2021 |
| 卷号 | 12 |
| 关键词 | Yak domestication 16S rDNA shotgun metagenomic sequencing fecal microbiota |
| 英文摘要 | Domestication is a key factor of genetic variation; however, the mechanism by which domestication alters gut microbiota is poorly understood. Here, to explore the variation in the structure, function, rapidly evolved genes (REGs), and enzyme profiles of cellulase and hemicellulose in fecal microbiota, we studied the fecal microbiota in wild, half-blood, and domestic yaks based on 16S rDNA sequencing, shotgun-metagenomic sequencing, and the measurement of short-chain-fatty-acids (SCFAs) concentration. Results indicated that wild and half-blood yaks harbored an increased abundance of the phylum Firmicutes and reduced abundance of the genus Akkermansia, which are both associated with efficient energy harvesting. The gut microbial diversity decreased in domestic yaks. The results of the shotgun-metagenomic sequencing showed that the wild yak harbored an increased abundance of microbial pathways that play crucial roles in digestion and growth of the host, whereas the domestic yak harbored an increased abundance of methane-metabolism-related pathways. Wild yaks had enriched amounts of REGs in energy and carbohydrate metabolism pathways, and possessed a significantly increased abundance of cellulases and endohemicellulases in the glycoside hydrolase family compared to domestic yaks. The concentrations of acetic, propionic, n-butyric, i-butyric, n-valeric, and i-valeric acid were highest in wild yaks. Our study displayed the domestic effect on the phenotype of composition, function in gut microbiota, and SCFAs associated with gut microbiota, which had a closely association with the growth performance of the livestock. These findings may enlighten the researchers to construct more links between economic characteristics and gut microbiota, and develop new commercial strains in livestock based on the biotechnology of gut microbiota. |
| 源URL | [http://210.75.249.4/handle/363003/60829]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Fu, Haibo,Zhang, Liangzhi,Fan, Chao,et al. Domestication Shapes the Community Structure and Functional Metagenomic Content of the Yak Fecal Microbiota[J]. FRONTIERS IN MICROBIOLOGY,2021,12. |
| APA | Fu, Haibo.,Zhang, Liangzhi.,Fan, Chao.,Liu, Chuanfa.,Li, Wenjing.,...&Zhang, Yanming.(2021).Domestication Shapes the Community Structure and Functional Metagenomic Content of the Yak Fecal Microbiota.FRONTIERS IN MICROBIOLOGY,12. |
| MLA | Fu, Haibo,et al."Domestication Shapes the Community Structure and Functional Metagenomic Content of the Yak Fecal Microbiota".FRONTIERS IN MICROBIOLOGY 12(2021). |
入库方式： OAI收割
来源：西北高原生物研究所
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