Genetic diversity and population structure of Tibetan sheep breeds determined by whole genome resequencing
文献类型：期刊论文
| 作者 | Li, Lei-Lei; Ma, Shi-Ke; Peng, Wei; Fang, You-Gui; Duo, Hai-Rui; Fu, Hong-Yun; Jia, Gong-Xue |
| 刊名 | TROPICAL ANIMAL HEALTH AND PRODUCTION
 |
| 出版日期 | 2021 |
| 卷号 | 53期号:1 |
| 关键词 | Tibetan sheep SNP Adaptability Candidate genes |
| 英文摘要 | Tibetan sheep is one of primitive Chinese sheep breeds, which achieved the divergence about 2500 years ago in Qinghai plateau region. According to different geographic conditions, especially altitudes, Tibetan sheep evolved into different breeds. In this study, we performed whole genome resequencing of 5 representative Tibetan sheep breeds. Comparative genomic analysis showed that they can be divided into different clades with a close genetic relationship. However, some genes with common selective regions were enriched for hypoxic adaptability in different breeds living at higher altitude, including GHR, BMP15, and CPLANE1. Furthermore, breed-specific selective regions about physical characteristics, especially wool growth, were found in genes such as BSND, USP24, NCAPG, and LCORL. This study could contribute to our understanding about trait formation and offer a reference for breeding of Tibetan sheep. |
| 源URL | [http://210.75.249.4/handle/363003/60850]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Li, Lei-Lei,Ma, Shi-Ke,Peng, Wei,et al. Genetic diversity and population structure of Tibetan sheep breeds determined by whole genome resequencing[J]. TROPICAL ANIMAL HEALTH AND PRODUCTION,2021,53(1). |
| APA | Li, Lei-Lei.,Ma, Shi-Ke.,Peng, Wei.,Fang, You-Gui.,Duo, Hai-Rui.,...&Jia, Gong-Xue.(2021).Genetic diversity and population structure of Tibetan sheep breeds determined by whole genome resequencing.TROPICAL ANIMAL HEALTH AND PRODUCTION,53(1). |
| MLA | Li, Lei-Lei,et al."Genetic diversity and population structure of Tibetan sheep breeds determined by whole genome resequencing".TROPICAL ANIMAL HEALTH AND PRODUCTION 53.1(2021). |
入库方式： OAI收割
来源：西北高原生物研究所
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