Associations between the exposure to persistent organic pollutants and type 2 diabetes in East China: A case-control study
文献类型：期刊论文
| 作者 | Han, Xu; Meng, Lingling; Li, Yingming; Li, An; Turyk, Mary E.; Yang, Ruiqiang; Wang, Pu; Xiao, Ke ; Zhao, Junpeng; Zhang, Jianqing
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| 刊名 | CHEMOSPHERE
 |
| 出版日期 | 2020-02 |
| 卷号 | 241页码:1-11 |
| ISSN号 | 0045-6535 |
| 关键词 | PCBs PBDEs Type 2 diabetes Case-control |
| 英文摘要 | Persistent organic pollutants (POPs) have been associated with a high risk of type 2 diabetes in different regions, although few studies from China have been published. We aimed to investigate the associations between POP exposure and type 2 diabetes in Chinese population. A total of 158 participants diagnosed with type 2 diabetes and 158 participants without the disorder from Shandong Province were enrolled in this case-control study during 2016-2017. Nine polychlorinated biphenyl congeners (PCBs) and 2 polybrominated diphenyl ethers with detectable levels in >= 75% of the participants were selected for data analysis. The results showed that POP exposure was significantly and positively associated with the risk of diabetes after adjusting for age, sex, BMI, triglycerides and total cholesterol. However, we did not observe an obvious modified effect of adiposity on the associations between POP exposure and diabetes in the present study, as strong associations between POPs and diabetes were observed in both the higher-BMI (BMI >= 25 kg/m(2)) and the lower-BMI (BMI<25 kg/m(2)) groups. POPs showed stronger associations with diabetes in males than in females. The odds ratio (OR) for the highest quartile of Sigma POPs was 6.97 for males, nearly two times higher than that for females (OR = 3.58). All these findings suggest that POP exposure may impact the risk of diabetes in Chinese population. (C) 2019 Elsevier Ltd. All rights reserved. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/44612]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Han, Xu,Meng, Lingling,Li, Yingming,et al. Associations between the exposure to persistent organic pollutants and type 2 diabetes in East China: A case-control study[J]. CHEMOSPHERE,2020,241:1-11. |
| APA | Han, Xu.,Meng, Lingling.,Li, Yingming.,Li, An.,Turyk, Mary E..,...&Jiang, Guibin.(2020).Associations between the exposure to persistent organic pollutants and type 2 diabetes in East China: A case-control study.CHEMOSPHERE,241,1-11. |
| MLA | Han, Xu,et al."Associations between the exposure to persistent organic pollutants and type 2 diabetes in East China: A case-control study".CHEMOSPHERE 241(2020):1-11. |
入库方式： OAI收割
来源：生态环境研究中心
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