Biomonitoring of chlorinated polyfluoroalkyl ether sulfonic acid in the general population in central and eastern China: Occurrence and associations with age/sex
文献类型：期刊论文
| 作者 | Jin, Qi; Ma, Jinghong; Shi, Yali; Chen, Chuyi; Wang, Yuan; Zhao, Erjuan; Cai, Yaqi; Qu, Guoqiang |
| 刊名 | ENVIRONMENT INTERNATIONAL
 |
| 出版日期 | 2020-11 |
| 卷号 | 144页码:1-11 |
| 关键词 | Cl-PFESA Human exposure Sex/age differences General population |
| ISSN号 | 0160-4120 |
| 英文摘要 | Although chlorinated polyfluoroalkyl ether sulfonic acid (Cl-PFESA) has been reported to be widespread in different environmental matrices of China, its exposure data in the general Chinese population are very limited. In the present study, the serum-to-whole-blood ratio was first assessed for 6:2 Cl-PFESA (mean/median: 2.07/1.82) based on its paired concentrations (n = 36), which allows a comparison in different blood matrices. The exposure levels of Cl-PFESAs in the general population were investigated by collecting blood samples (n = 1516) from residents of seven cities in central and eastern China. 6:2 Cl-PFESA was observed as the third-highest contributing polyfluoroalkyl substance (PFAS) (8.69%), with the median concentration at 2.18 ng/mL, indicating its importance for assessing the human exposure risks of PFASs. The regional difference between 6:2 Cl-PFESA and perfluorooctane sulfonate (PFOS) can be explained by their use pattern in China. Overall, similar to PFOS, 6:2 Cl-PFESA displays significantly increasing levels with increasing age for both males and females, with significantly higher levels in males. However, a significant sex dependence was found for 6:2 Cl-PFESA in one specific age group (41-60), while there was no significance in the other groups although males display higher levels than females. Our study provides robust data regarding human exposure to 6:2 Cl-PFESA in the general population in central and eastern China. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/44620]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Jin, Qi,Ma, Jinghong,Shi, Yali,et al. Biomonitoring of chlorinated polyfluoroalkyl ether sulfonic acid in the general population in central and eastern China: Occurrence and associations with age/sex[J]. ENVIRONMENT INTERNATIONAL,2020,144:1-11. |
| APA | Jin, Qi.,Ma, Jinghong.,Shi, Yali.,Chen, Chuyi.,Wang, Yuan.,...&Qu, Guoqiang.(2020).Biomonitoring of chlorinated polyfluoroalkyl ether sulfonic acid in the general population in central and eastern China: Occurrence and associations with age/sex.ENVIRONMENT INTERNATIONAL,144,1-11. |
| MLA | Jin, Qi,et al."Biomonitoring of chlorinated polyfluoroalkyl ether sulfonic acid in the general population in central and eastern China: Occurrence and associations with age/sex".ENVIRONMENT INTERNATIONAL 144(2020):1-11. |
入库方式： OAI收割
来源：生态环境研究中心
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