Identification of volatile active components in Acori Tatarinowii Rhizome essential oil from different regions in China by C6 glioma cells
文献类型：期刊论文
| 作者 | Yan, Lu; Liu, Zhanzhan; Xu, Li; Qian, Yiyun; Song, Pingping; Wei, Min |
| 刊名 | BMC COMPLEMENTARY MEDICINE AND THERAPIES
 |
| 出版日期 | 2020-08-17 |
| 卷号 | 20期号:1页码:1-9 |
| 关键词 | Acori Tatarinowii Rhizome Essential oil Region difference Volatile active component Neuroprotective |
| 英文摘要 | Background Acori Tatarinowii Rhizome (ATR) is a well-recognized Chinese herbal medicine prescribed to treat neurological disorders. The essential oil (ATEO) is considered as the active fraction of ATR and the content of ATEO is used as the only indicator for ATR content determination. The quality of ATEO varies widely due to region difference; however, little is known about how to study ATEO quality chemically and biologically in response to region difference. Thus, it is of great importance to identify volatile active components in ATEO to conduct quality study. In this study, we analyzed ATEO from different regions in China using chemical component analysis combined with biological activity evaluation. Methods GC-MS was used to obtain different volatile component profiles of ATEO and significantly changed volatile components were screened out. The neuroprotective activities of ATEO, including anti-oxidation, anti-inflammation and neurotrophic functions, were revealed in C6 glioma cells. The correlation study between the bioactivities and the components was performed. Results 57 volatile components, including terpenoids, phenylpropanoids, aromatic compounds, and other aliphatic compounds, were identified. 8 volatile components (beta-asarone, cis-methyl isoeugenol, gamma-asarone, methyleugenol, calarene, longifolene, beta-caryophyllene and caryophyllene oxide) from ATEO were significantly changed due to region difference and 2 of them (beta-asarone and gamma-asarone) showed strong correlation with neuroprotective activities. Conclusions Our results reveal that ATEO from different regions in China show great changes in chemical composition and biological activity. Moreover, phenylpropanoids (beta-asarone and gamma-asarone) present strong correlation with the bioactivities, which are considered as volatile active components in ATEO. The findings will be useful for the development of quality study of ATEO. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/44709]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Yan, Lu,Liu, Zhanzhan,Xu, Li,et al. Identification of volatile active components in Acori Tatarinowii Rhizome essential oil from different regions in China by C6 glioma cells[J]. BMC COMPLEMENTARY MEDICINE AND THERAPIES,2020,20(1):1-9. |
| APA | Yan, Lu,Liu, Zhanzhan,Xu, Li,Qian, Yiyun,Song, Pingping,&Wei, Min.(2020).Identification of volatile active components in Acori Tatarinowii Rhizome essential oil from different regions in China by C6 glioma cells.BMC COMPLEMENTARY MEDICINE AND THERAPIES,20(1),1-9. |
| MLA | Yan, Lu,et al."Identification of volatile active components in Acori Tatarinowii Rhizome essential oil from different regions in China by C6 glioma cells".BMC COMPLEMENTARY MEDICINE AND THERAPIES 20.1(2020):1-9. |
入库方式： OAI收割
来源：生态环境研究中心
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。