Metabolism of SCCPs and MCCPs in Suspension Rice Cells Based on Paired Mass Distance (PMD) Analysis
文献类型：期刊论文
| 作者 | Chen, Weifang; Yu, Miao; Zhang, Qing; Hou, Xingwang ; Kong, Wenqian; Wei, Linfeng; Mao, Xiaowei; Liu, Jiyan; Schnoor, Jerald L.; Jiang, Guibin
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| 刊名 | ENVIRONMENTAL SCIENCE & TECHNOLOGY
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| 出版日期 | 2020-08-18 |
| 卷号 | 54期号:16页码:9990-9999 |
| ISSN号 | 0013-936X |
| 英文摘要 | Short-chain and medium-chain chlorinated paraffins (SCCPs and MCCPs) are mixtures of complex chemical compounds with intensive usage. They are frequently detected in various environmental samples. However, the interaction between CPs and plants, especially the biotransformation behaviors of CPs within plants, is poorly understood. In this study, 1,2,5,6,9,10-hexachlorodecane (CP-4, a typical standard of individual SCCP congeners) and 52%-MCCP (a commercial mixture standard of MCCPs with 52% chlorine content by mass) were selected as representative chemicals to explore the metabolic behaviors of SCCPs and MCCPs using suspension rice cell culture exposure systems. Both 79.53% and 40.70% of CP-4 and 52%-MCCP were metabolized by suspension rice cells, respectively. A complementary suspected screening strategy based on the pair mass distances (PMD) analysis algorithm was used to study the metabolism of CPs mediated by the plant cells. Forty and 25 metabolic products for CP-4 and 52%-MCCP, respectively, were identified, including (multi-) hydroxylation, dechlorination, -HCI- elimination metabolites, (hydroxylation-) sulfation, and glycosylation conjugates. Here, we propose a comprehensive metabolic molecular network and provide insight on degradation pathways of SCCPs and MCCPs in plants for the first time, aiding in further understanding of the transformation behaviors of CPs. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/44733]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Chen, Weifang,Yu, Miao,Zhang, Qing,et al. Metabolism of SCCPs and MCCPs in Suspension Rice Cells Based on Paired Mass Distance (PMD) Analysis[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2020,54(16):9990-9999. |
| APA | Chen, Weifang.,Yu, Miao.,Zhang, Qing.,Hou, Xingwang.,Kong, Wenqian.,...&Jiang, Guibin.(2020).Metabolism of SCCPs and MCCPs in Suspension Rice Cells Based on Paired Mass Distance (PMD) Analysis.ENVIRONMENTAL SCIENCE & TECHNOLOGY,54(16),9990-9999. |
| MLA | Chen, Weifang,et al."Metabolism of SCCPs and MCCPs in Suspension Rice Cells Based on Paired Mass Distance (PMD) Analysis".ENVIRONMENTAL SCIENCE & TECHNOLOGY 54.16(2020):9990-9999. |
入库方式： OAI收割
来源：生态环境研究中心
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