The Crucial Role of Environmental Coronas in Determining the Biological Effects of Engineered Nanomaterials
文献类型：期刊论文
| 作者 | Xu, Lining; Xu, Ming; Wang, Ruixia; Yin, Yongguang; Lynch, Iseult; Liu, Sijin |
| 刊名 | SMALL
 |
| 出版日期 | 2020-09 |
| 卷号 | 16期号:36页码:1-6 |
| 关键词 | aquatic environment aquatic organism ecotoxicological effect engineered nanomaterials environmental corona |
| ISSN号 | 1613-6810 |
| 英文摘要 | In aquatic environments, a large number of ecological macromolecules (e.g., natural organic matter (NOM), extracellular polymeric substances (EPS), and proteins) can adsorb onto the surface of engineered nanomaterials (ENMs) to form a unique environmental corona. The presence of environmental corona as an eco-nano interface can significantly alter the bioavailability, biocompatibility, and toxicity of pristine ENMs to aquatic organisms. However, as an emerging field, research on the impact of the environmental corona on the fate and behavior of ENMs in aquatic environments is still in its infancy. To promote a deeper understanding of its importance in driving or moderating ENM toxicity, this study systemically recapitulates the literature of representative types of macromolecules that are adsorbed onto ENMs; these constitute the environmental corona, including NOM, EPS, proteins, and surfactants. Next, the ecotoxicological effects of environmental corona-coated ENMs on representative aquatic organisms at different trophic levels are discussed in comparison to pristine ENMs, based on the reported studies. According to this analysis, molecular mechanisms triggered by pristine and environmental corona-coated ENMs are compared, including membrane adhesion, membrane damage, cellular internalization, oxidative stress, immunotoxicity, genotoxicity, and reproductive toxicity. Finally, current knowledge gaps and challenges in this field are discussed from the ecotoxicology perspective. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/44823]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Xu, Lining,Xu, Ming,Wang, Ruixia,et al. The Crucial Role of Environmental Coronas in Determining the Biological Effects of Engineered Nanomaterials[J]. SMALL,2020,16(36):1-6. |
| APA | Xu, Lining,Xu, Ming,Wang, Ruixia,Yin, Yongguang,Lynch, Iseult,&Liu, Sijin.(2020).The Crucial Role of Environmental Coronas in Determining the Biological Effects of Engineered Nanomaterials.SMALL,16(36),1-6. |
| MLA | Xu, Lining,et al."The Crucial Role of Environmental Coronas in Determining the Biological Effects of Engineered Nanomaterials".SMALL 16.36(2020):1-6. |
入库方式： OAI收割
来源：生态环境研究中心
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