中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Pkweb: An online application for pharmacokinetic data analysis

文献类型:期刊论文

作者Dong, Zhaomin; Fan, Xiarui; Fan, Wenhong; Chang, Hong; Xu, Yilu; Li, Tong; Su, Ming
刊名ENVIRONMENTAL TECHNOLOGY & INNOVATION
出版日期2020-08
卷号19页码:1-6
关键词Pharmacokinetic Pkweb R shiny Online application Prior parameters
ISSN号2352-1864
英文摘要This research presents a web-based application, pkweb (https://pkweb.hhra.net), with a user-friendly interface and a range of functions for pharmacokinetic (PK) data analysis. Capabilities include simulation of PK data, which integrates 27 modules (e.g., intravenous (IV) bolus injection, IV infusion and extravascular administration) and modeling the fitness of PK data. The pkweb tool provides different solutions for various conditions, such as compartmental analysis (CA) under single dosing, non-compartmental analysis (NCA) under single dosing and CA under multiple dosing. Compared to other tools, a unique feature of this tool is the ability to set boundaries for the parameters of each model. This newly released application promises to facilitate both toxicokinetic and pharmacokinetic data analysis. (C) 2020 Elsevier B.V. All rights reserved.
源URL[http://ir.rcees.ac.cn/handle/311016/44976]  
专题生态环境研究中心_环境水质学国家重点实验室
推荐引用方式
GB/T 7714
Dong, Zhaomin,Fan, Xiarui,Fan, Wenhong,et al. Pkweb: An online application for pharmacokinetic data analysis[J]. ENVIRONMENTAL TECHNOLOGY & INNOVATION,2020,19:1-6.
APA Dong, Zhaomin.,Fan, Xiarui.,Fan, Wenhong.,Chang, Hong.,Xu, Yilu.,...&Su, Ming.(2020).Pkweb: An online application for pharmacokinetic data analysis.ENVIRONMENTAL TECHNOLOGY & INNOVATION,19,1-6.
MLA Dong, Zhaomin,et al."Pkweb: An online application for pharmacokinetic data analysis".ENVIRONMENTAL TECHNOLOGY & INNOVATION 19(2020):1-6.

入库方式: OAI收割

来源:生态环境研究中心

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