Antibiotic Resistance in the Collembolan Gut Microbiome Accelerated by the Nonantibiotic Drug Carbamazepine
文献类型：期刊论文
| 作者 | Wang, Yi-Fei; Qiao, Min ; Zhu, Dong; Zhu, Yong-Guan
|
| 刊名 | ENVIRONMENTAL SCIENCE & TECHNOLOGY
 |
| 出版日期 | 2020-09-01 |
| 卷号 | 54期号:17页码:10744-10752 |
| ISSN号 | 0013-936X |
| 英文摘要 | The effects of pharmaceuticals as emerging contaminants in soil on the gut microbiome and antibiotic resistome in nontarget soil fauna are largely elusive. In this study, we explored the composition of the bacterial community and the presence of antibiotic resistance genes (ARGs) in the gut of the model soil collembolan (Folsomia candida) upon antiepileptic drug carbamazepine (CBZ) and antibiotic tetracycline (TC) exposure. Results showed that, individually or in combination, exposure to TC or CBZ significantly altered the gut community structure of F. candida, causing some enrichment of the bacteria associated with xenobiotic metabolism, such as Arthrobacter, Achromobacter, Gordonia, and Shinella. More importantly, oral exposure to the nonantibiotic drug CBZ enhanced the abundance and diversity of ARGs in the gut of F. candida, especially for the beta-lactams and multidrug resistance genes. Our results revealed that the most likely hosts of ARGs in the gut of F. candida were Proteobacteria and Actinobacteria. The significant positive correlation between mobile genetic elements (MGEs) and ARGs indicated the potential risk of ARGs transmission in the gut of F. candida. Overall, the nonantibiotic CBZ is likely to disturb the gut microbiota of nontarget soil fauna such as collembolans, thereby enhancing the dissemination of ARGs. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/44213]  |
| 专题 | 生态环境研究中心_城市与区域生态国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Wang, Yi-Fei,Qiao, Min,Zhu, Dong,et al. Antibiotic Resistance in the Collembolan Gut Microbiome Accelerated by the Nonantibiotic Drug Carbamazepine[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2020,54(17):10744-10752. |
| APA | Wang, Yi-Fei,Qiao, Min,Zhu, Dong,&Zhu, Yong-Guan.(2020).Antibiotic Resistance in the Collembolan Gut Microbiome Accelerated by the Nonantibiotic Drug Carbamazepine.ENVIRONMENTAL SCIENCE & TECHNOLOGY,54(17),10744-10752. |
| MLA | Wang, Yi-Fei,et al."Antibiotic Resistance in the Collembolan Gut Microbiome Accelerated by the Nonantibiotic Drug Carbamazepine".ENVIRONMENTAL SCIENCE & TECHNOLOGY 54.17(2020):10744-10752. |
入库方式： OAI收割
来源：生态环境研究中心
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。