The Great Oxidation Event expanded the genetic repertoire of arsenic metabolism and cycling
文献类型：期刊论文
| 作者 | Chen, Song-Can; Sun, Guo-Xin ; Yan, Yu; Konstantinidis, Konstantinos T.; Zhang, Si-Yu; Deng, Ye; Li, Xiao-Min; Cui, Hui-Ling; Musat, Florin; Popp, Denny
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| 刊名 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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| 出版日期 | 2020-05-12 |
| 卷号 | 117期号:19页码:10414-10421 |
| 关键词 | arsenic detoxification evolution oxygen biogeochemistry |
| ISSN号 | 0027-8424 |
| 英文摘要 | The rise of oxygen on the early Earth about 2.4 billion years ago reorganized the redox cycle of harmful metal(loids), including that of arsenic, which doubtlessly imposed substantial barriers to the physiology and diversification of life. Evaluating the adaptive biological responses to these environmental challenges is inherently difficult because of the paucity of fossil records. Here we applied molecular clock analyses to 13 gene families participating in principal pathways of arsenic resistance and cycling, to explore the nature of early arsenic biogeocycles and decipher feedbacks associated with planetary oxygenation. Our results reveal the advent of nascent arsenic resistance systems under the anoxic environment predating the Great Oxidation Event (GOE), with the primary function of detoxifying reduced arsenic compounds that were abundant in Archean environments. To cope with the increased toxicity of oxidized arsenic species that occurred as oxygen built up in Earth's atmosphere, we found that parts of preexisting detoxification systems for trivalent arsenicals were merged with newly emerged pathways that originated via convergent evolution. Further expansion of arsenic resistance systems was made feasible by incorporation of oxygen-dependent enzymatic pathways into the detoxification network. These genetic innovations, together with adaptive responses to other redoxsensitive metals, provided organisms with novel mechanisms for adaption to changes in global biogeocycles that emerged as a consequence of the GOE. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/44483]  |
| 专题 | 生态环境研究中心_城市与区域生态国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Chen, Song-Can,Sun, Guo-Xin,Yan, Yu,et al. The Great Oxidation Event expanded the genetic repertoire of arsenic metabolism and cycling[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2020,117(19):10414-10421. |
| APA | Chen, Song-Can.,Sun, Guo-Xin.,Yan, Yu.,Konstantinidis, Konstantinos T..,Zhang, Si-Yu.,...&Zhu, Yong-Guan.(2020).The Great Oxidation Event expanded the genetic repertoire of arsenic metabolism and cycling.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,117(19),10414-10421. |
| MLA | Chen, Song-Can,et al."The Great Oxidation Event expanded the genetic repertoire of arsenic metabolism and cycling".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117.19(2020):10414-10421. |
入库方式： OAI收割
来源：生态环境研究中心
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