Three organophosphate flame retardants (OPFRs) reduce sperm quality in Chinese rare minnows (Gobiocypris rarus)
文献类型：期刊论文
| 作者 | Chen, Rui; Hong, Xiangsheng; Yan, Saihong; Zha, Jinmiao |
| 刊名 | ENVIRONMENTAL POLLUTION
 |
| 出版日期 | 2020-08 |
| 卷号 | 263页码:1-8 |
| ISSN号 | 0269-7491 |
| 关键词 | Na+/K+ ATPase RNA-seq Endocrine disruption Sperm velocity |
| 英文摘要 | Organophosphate flame retardants (OPFRs) are widespread in the aquatic environment, but the effects of these chemicals on reproductive toxicity are far from clear. In this study, sperm quality in adult male Chinese rare minnows after exposure to tris-(2-butoxyethyl) phosphate (TBOEP), tris-(1,3-dichloro-2-propyl) phosphate (TDCIPP), and triphenyl phosphate (TPHP) was investigated. No obvious change in sperm concentration and vitality was observed after treatments, whereas significant changes in sperm velocity and morphology were found following all treatments (P < 0.05). Moreover, OPFR exposure significantly increased the apoptosis ratios in testis cells. Analysis of the transcriptomic data revealed that Na+/K+ ATPase (NKA) related genes were significantly downregulated, and the NKA enzyme activities after all treatments were significantly inhibited (P < 0.05). However, no obvious change in hormone levels in the groups exposed to TBOEP and TDCIPP was observed. These findings indicate that the OPFR-induced reduction of sperm quality might be due to the effects of OPFRs on NKA enzyme instead of changes in hormone levels. (C) 2020 Elsevier Ltd. All rights reserved. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/45371]  |
| 专题 | 生态环境研究中心_中国科学院饮用水科学与技术重点实验室 |
| 推荐引用方式 GB/T 7714 | Chen, Rui,Hong, Xiangsheng,Yan, Saihong,et al. Three organophosphate flame retardants (OPFRs) reduce sperm quality in Chinese rare minnows (Gobiocypris rarus)[J]. ENVIRONMENTAL POLLUTION,2020,263:1-8. |
| APA | Chen, Rui,Hong, Xiangsheng,Yan, Saihong,&Zha, Jinmiao.(2020).Three organophosphate flame retardants (OPFRs) reduce sperm quality in Chinese rare minnows (Gobiocypris rarus).ENVIRONMENTAL POLLUTION,263,1-8. |
| MLA | Chen, Rui,et al."Three organophosphate flame retardants (OPFRs) reduce sperm quality in Chinese rare minnows (Gobiocypris rarus)".ENVIRONMENTAL POLLUTION 263(2020):1-8. |
入库方式： OAI收割
来源：生态环境研究中心
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。