Reversion of malignant phenotypes of human glioblastoma cells by β -elemene through β -catenin-mediated regulation of stemness-, differentiation- and epithelial-to-mesenchymal transition-related molecules
文献类型：期刊论文
| 作者 | Tingzhun Zhu; Xiaoming Li; Lihan Luo; Xiaogang Wang; Zhiqing Li; Peng Xie; Xu Gao; Zhenquan Song; Jingyuan Su; Guobiao Liang |
| 刊名 | Journal of Translational Medicine
 |
| 出版日期 | 2015 |
| 卷号 | 13期号:1 |
| ISSN号 | 1479-5876 |
| 其他题名 | Reversion of malignant phenotypes of human glioblastoma cells by β -elemene through β -catenin-mediated regulation of stemness-, differentiation- and epithelial-to-mesenchymal transition-related molecules |
| 英文摘要 | Glioblastoma is the most common and lethal type of primary brain tumor. β -Elemene, a natural plant drug extracted from Curcuma wenyujin , has shown strong anti-tumor effects in various tumors with low toxicity. However, the effects of β -elemene on malignant phenotypes of human glioblastoma cells remain to be elucidated. Here we evaluated the effects of β -elemene on cell proliferation, survival, stemness, differentiation and the epithelial-to-mesenchymal transition (EMT) in vitro and in vivo, and investigated the mechanisms underlying these effects. |
| 语种 | 英语 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/159346]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 作者单位 | Institute of Metal Research, Chinese Academy of Sciences |
| 推荐引用方式 GB/T 7714 | Tingzhun Zhu,Xiaoming Li,Lihan Luo,et al. Reversion of malignant phenotypes of human glioblastoma cells by β -elemene through β -catenin-mediated regulation of stemness-, differentiation- and epithelial-to-mesenchymal transition-related molecules[J]. Journal of Translational Medicine,2015,13(1). |
| APA | Tingzhun Zhu.,Xiaoming Li.,Lihan Luo.,Xiaogang Wang.,Zhiqing Li.,...&Guobiao Liang.(2015).Reversion of malignant phenotypes of human glioblastoma cells by β -elemene through β -catenin-mediated regulation of stemness-, differentiation- and epithelial-to-mesenchymal transition-related molecules.Journal of Translational Medicine,13(1). |
| MLA | Tingzhun Zhu,et al."Reversion of malignant phenotypes of human glioblastoma cells by β -elemene through β -catenin-mediated regulation of stemness-, differentiation- and epithelial-to-mesenchymal transition-related molecules".Journal of Translational Medicine 13.1(2015). |
入库方式： OAI收割
来源：金属研究所
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