In vivo degradation behaviour and bone response of a new Mg-rare earth alloy immobilized in a rat femoral model
文献类型：期刊论文
| 作者 | Wang, Haijian4; Kumazawa, Takashi4; Zhang, Ying4; Wang, Haiwei1,2; Ju, Dongying3,4,5 |
| 刊名 | MATERIALS TODAY COMMUNICATIONS
 |
| 出版日期 | 2021-03-01 |
| 卷号 | 26页码:12 |
| 关键词 | Mg-RE sheet In vivo Amorphous Degradable Bone response |
| ISSN号 | 2352-4928 |
| DOI | 10.1016/j.mtcomm.2020.101727 |
| 通讯作者 | Ju, Dongying(dyju@sit.ac.jp) |
| 英文摘要 | A new type of Mg-rare earth (Ce, La) and the AZ31 alloy sheets were prepared by vertical twin-roll casting (TRC) technology under identical casting conditions, and their microstructural features, degradation behaviours and bone responses were investigated. The microstructural characterization showed that the Mg-RE (rare earth) exhibited a higher amorphous forming ability than the AZ31. Moreover, the results of electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization indicated that the Mg-RE sheets displayed a higher corrosion resistance compared with the AZ31 sheets. Additionally, the Ti, Mg-RE and AZ31 sheet implants were immobilized and implanted in a rat femur model to observe degradation behavior during 16 weeks. in vivo tests showed that no significant change in the femur surrounding the Ti group, which excluded the external factor that the new bone formation resulting from bone remodeling. Furthermore, the Mg-RE group induced more newly formed bones, which met the necessary conditions for the prevention of pathological fractures. Therefore, the novel Mg-RE alloy appear to hold a healing candidate as the biodegradable implant material. |
| 资助项目 | High-Tech Research Center and Animal experiment Project[2019-5] |
| WOS研究方向 | Materials Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000634334200002 |
| 出版者 | ELSEVIER |
| 资助机构 | High-Tech Research Center and Animal experiment Project |
| 源URL | [http://ir.imr.ac.cn/handle/321006/161959]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 通讯作者 | Ju, Dongying |
| 作者单位 | 1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China 2.Univ Sci & Technol China Hefei, Sch Mat Sci & Engn, Hefei 230026, Peoples R China 3.Univ Sci & Technol Liaoning, Sch Mat & Met, Anshan 114051, Peoples R China 4.Saitama Inst Technol, Dept High Tech Res Ctr, Fusaiji 1690, Fukaya 3690293, Japan 5.Ningbo Haizhi Inst Mat Ind Innovat, Ningbo 315000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Haijian,Kumazawa, Takashi,Zhang, Ying,et al. In vivo degradation behaviour and bone response of a new Mg-rare earth alloy immobilized in a rat femoral model[J]. MATERIALS TODAY COMMUNICATIONS,2021,26:12. |
| APA | Wang, Haijian,Kumazawa, Takashi,Zhang, Ying,Wang, Haiwei,&Ju, Dongying.(2021).In vivo degradation behaviour and bone response of a new Mg-rare earth alloy immobilized in a rat femoral model.MATERIALS TODAY COMMUNICATIONS,26,12. |
| MLA | Wang, Haijian,et al."In vivo degradation behaviour and bone response of a new Mg-rare earth alloy immobilized in a rat femoral model".MATERIALS TODAY COMMUNICATIONS 26(2021):12. |
入库方式： OAI收割
来源：金属研究所
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