An Amorphous Peri-Implant Ligament with Combined Osteointegration and Energy-Dissipation
文献类型：期刊论文
| 作者 | Hou, Junyu1; Xiao, Zuohui2; Liu, Zengqian3; Zhao, Hewei1; Zhu, Yankun3; Guo, Lin1; Zhang, Zhefeng3; Ritchie, Robert O.4; Wei, Yan2; Deng, Xuliang2 |
| 刊名 | ADVANCED MATERIALS
 |
| 出版日期 | 2021-09-27 |
| 页码 | 12 |
| 关键词 | amorphous titania nanotubes energy dissipation osteointegration tooth periodontal ligament |
| ISSN号 | 0935-9648 |
| DOI | 10.1002/adma.202103727 |
| 通讯作者 | Guo, Lin(guolin@buaa.edu.cn) ; Ritchie, Robert O.(roritchie@lbl.gov) ; Wei, Yan(kqweiyan@bjmu.edu.cn) ; Deng, Xuliang(kqdengxuliang@bjmu.edu.cn) |
| 英文摘要 | Progress toward developing metal implants as permanent hard-tissue substitutes requires both osteointegration to achieve load-bearing support, and energy-dissipation to prevent overload-induced bone resorption. However, in existing implants these two properties can only be achieved separately. Optimized by natural evolution, tooth-periodontal-ligaments with fiber-bundle structures can efficiently orchestrate load-bearing and energy dissipation, which make tooth-bone complexes survive extremely high occlusion loads (>300 N) for prolonged lifetimes. Here, a bioinspired peri-implant ligament with simultaneously enhanced osteointegration and energy-dissipation is presented, which is based on the periodontium-mimetic architecture of a polymer-infiltrated, amorphous, titania nanotube array. The artificial ligament not only provides exceptional osteoinductivity owing to its nanotopography and beneficial ingredients, but also produces periodontium-similar energy dissipation due to the complexity of the force transmission modes and interface sliding. The ligament increases bone-implant contact by more than 18% and simultaneously reduces the effective stress transfer from implant to peri-implant bone by approximate to 30% as compared to titanium implants, which as far as is known has not previously been achieved. It is anticipated that the concept of an artificial ligament will open new possibilities for developing high-performance implanted materials with increased lifespans. |
| 资助项目 | National Key R&D Program of China[2020YFA0710401] ; National Key R&D Program of China[2020YFA0710403] ; National Key R&D Program of China[2020YFA0710404] ; National Key R&D Program of China[2018YFC1105301] ; National Key R&D Program of China[2018YFC1105302] ; National Key R&D Program of China[2018YFC1105304] ; National Natural Science Foundation of China[51532001] ; National Natural Science Foundation of China[51772011] ; National Natural Science Foundation of China[51802010] ; National Natural Science Foundation of China[52073008] ; National Natural Science Foundation of China[81922019] ; National Natural Science Foundation of China[51772006] ; National Natural Science Foundation of China[31670993] ; National Youth Topnotch Talent Support Program[QNBJ2019-3] ; Beijing Municipal Science & Technology Commission Projects[Z181100002018001] ; Peking University Medicine Fund[PKU2020LCXQ009] |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000700091200001 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 资助机构 | National Key R&D Program of China ; National Natural Science Foundation of China ; National Youth Topnotch Talent Support Program ; Beijing Municipal Science & Technology Commission Projects ; Peking University Medicine Fund |
| 源URL | [http://ir.imr.ac.cn/handle/321006/166763]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 通讯作者 | Guo, Lin; Ritchie, Robert O.; Wei, Yan; Deng, Xuliang |
| 作者单位 | 1.Beihang Univ, Sch Chem, Beijing Adv Innovat Ctr Biomed Engn, Beijing 100191, Peoples R China 2.Peking Univ Sch & Hosp Stomatol, Dept Geriatr Dent, Natl Engn Lab Digital & Mat Technol Stomatol, NMPA Key Lab Dent Mat, Beijing 100081, Peoples R China 3.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China 4.Univ Calif Berkeley, Dept Mat Sci & Engn, Berkeley, CA 94720 USA |
| 推荐引用方式 GB/T 7714 | Hou, Junyu,Xiao, Zuohui,Liu, Zengqian,et al. An Amorphous Peri-Implant Ligament with Combined Osteointegration and Energy-Dissipation[J]. ADVANCED MATERIALS,2021:12. |
| APA | Hou, Junyu.,Xiao, Zuohui.,Liu, Zengqian.,Zhao, Hewei.,Zhu, Yankun.,...&Deng, Xuliang.(2021).An Amorphous Peri-Implant Ligament with Combined Osteointegration and Energy-Dissipation.ADVANCED MATERIALS,12. |
| MLA | Hou, Junyu,et al."An Amorphous Peri-Implant Ligament with Combined Osteointegration and Energy-Dissipation".ADVANCED MATERIALS (2021):12. |
入库方式： OAI收割
来源：金属研究所
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