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Polyoxygenated cembranoids from the Hainan soft coral Lobophytum crassum

文献类型：期刊论文

作者Yin, Fang-Zhou1,2,3; Yao, Li-Gong1; Zhang, Zai-Yong1; Wang, Jian-Rong1; Wang, Hong2,3; Guo, Yue-Wei1,2,3
刊名TETRAHEDRON
出版日期2021-06-18
卷号90页码:7
关键词Soft coral Marine natural products Cembranoids Stereochemistry
ISSN号0040-4020
DOI10.1016/j.tet.2021.132204
通讯作者Wang, Hong(hongw@zjut.edu.cn) ; Guo, Yue-Wei(ywguo@simm.ac.cn)
英文摘要Five new uncommon cembranoids, named lobophycrasins A-D (1 and 3-5) and (-)-humilisin A (2), together with a known related one (6), have been isolated from Hainan soft coral Lobophytum crassum. Their structures were elucidated by extensive spectroscopic analysis, NMR calculation with DP4+ probability analysis, TDDFT-ECD (time-dependent density functional theory-electronic circular dichroism) calculations and comparison with the reported data. Further, with the aid of X-ray diffraction analysis, the structure of lobocrasol (6), which was announced possessing novel unprecedented skeleton, was firmly revised as 6a. In addition, a plausible biogenetic connection among these isolates was also proposed. (C) 2021 Elsevier Ltd. All rights reserved.
WOS关键词DITERPENES
资助项目Natural Science Foundation of China[81991521] ; National Key Research and Development Program of China[2018YFC0310903] ; SKLDR/SIMM Project[SIMM2103ZZ-06]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000663120400013
出版者PERGAMON-ELSEVIER SCIENCE LTD
源URL[http://119.78.100.183/handle/2S10ELR8/297131]  
专题新药研究国家重点实验室
通讯作者Wang, Hong; Guo, Yue-Wei
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China
2.Zhejiang Univ Technol, Collaborat Innovat Ctr Yangtze River Delta Reg Gr, Hangzhou 310014, Peoples R China
3.Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310014, Peoples R China
推荐引用方式
GB/T 7714		 Yin, Fang-Zhou,Yao, Li-Gong,Zhang, Zai-Yong,et al. Polyoxygenated cembranoids from the Hainan soft coral Lobophytum crassum[J]. TETRAHEDRON,2021,90:7.
APA Yin, Fang-Zhou,Yao, Li-Gong,Zhang, Zai-Yong,Wang, Jian-Rong,Wang, Hong,&Guo, Yue-Wei.(2021).Polyoxygenated cembranoids from the Hainan soft coral Lobophytum crassum.TETRAHEDRON,90,7.
MLA Yin, Fang-Zhou,et al."Polyoxygenated cembranoids from the Hainan soft coral Lobophytum crassum".TETRAHEDRON 90(2021):7.

入库方式： OAI收割

来源：上海药物研究所

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