Clerodenoids A-F: C-ring Aromatized and/or Rearranged Abietane Diterpenoids from Clerodendrum chinense var. simplex
文献类型：期刊论文
| 作者 | Qi, Jingjing1; Zhang, Yan2; Liu, Qunfang2 ; Liu, Hongchun2; Fan, Yaoyue2; Yue, Jianmin1,2
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| 刊名 | CHINESE JOURNAL OF CHEMISTRY
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| 出版日期 | 2021-05-30 |
| 页码 | 7 |
| 关键词 | Clerodendrum chinense Natural products Diterpenoids Structural elucidation Antiproliferative activities |
| ISSN号 | 1001-604X |
| DOI | 10.1002/cjoc.202100117 |
| 通讯作者 | Liu, Hongchun(hchliu@simm.ac.cn) ; Fan, Yaoyue(s040500290@126.com) ; Yue, Jianmin(jmyue@simm.ac.cn) |
| 英文摘要 | Main observation and conclusion As part of our continuing efforts toward the discovery of the biologically active diterpenoids from medicinal plants, six new C-ring aromatized abietane diterpenoids, clerodenoids A-F (1-6), were isolated from Clerodendrum chinense. These C-ring aromatized compounds mainly belonged to the rearranged abietane skeletons of 17(15 -> 16)-abeo-abietane (2-4) and 17(15 -> 16), 18(4 -> 3)-diabeo-abietane (5 and 6). Their structures were elucidated by extensive spectroscopic data, X-ray crystallography, and ECD calculation. Compounds 5 and 6 displayed strong antiproliferative activities against A549 and HL-60 cell lines. |
| WOS关键词 | PHENYLPROPANOID GLYCOSIDES ; TRICHOTOMUM |
| 资助项目 | National Natural Science Foundation of China[81872758] ; National Natural Science Foundation of China[21772213] ; Shanghai Rising-Star program Foundation (SCST)[19QA1410800] ; Youth Innovation Promotion Association, Chinese Academy of Sciences |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000656175700001 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/297208]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Liu, Hongchun; Fan, Yaoyue; Yue, Jianmin |
| 作者单位 | 1.Nanjing Univ Chinese Med, Sch Chinese Mat Med, 138 Xianlin Rd, Nanjing 210023, Jiangsu, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qi, Jingjing,Zhang, Yan,Liu, Qunfang,et al. Clerodenoids A-F: C-ring Aromatized and/or Rearranged Abietane Diterpenoids from Clerodendrum chinense var. simplex[J]. CHINESE JOURNAL OF CHEMISTRY,2021:7. |
| APA | Qi, Jingjing,Zhang, Yan,Liu, Qunfang,Liu, Hongchun,Fan, Yaoyue,&Yue, Jianmin.(2021).Clerodenoids A-F: C-ring Aromatized and/or Rearranged Abietane Diterpenoids from Clerodendrum chinense var. simplex.CHINESE JOURNAL OF CHEMISTRY,7. |
| MLA | Qi, Jingjing,et al."Clerodenoids A-F: C-ring Aromatized and/or Rearranged Abietane Diterpenoids from Clerodendrum chinense var. simplex".CHINESE JOURNAL OF CHEMISTRY (2021):7. |
入库方式： OAI收割
来源：上海药物研究所
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