Horienoids A and B, Two Heterocoupled Sesquiterpenoid Dimers from Hedyosmum orientale
文献类型:期刊论文
作者 | Fan, Yao-Yue1; Gan, Li-She2,3; Chen, Shi-Xin2; Gong, Qi4; Zhang, Hai-Yan4![]() ![]() |
刊名 | JOURNAL OF ORGANIC CHEMISTRY
![]() |
出版日期 | 2021-08-20 |
卷号 | 86期号:16页码:11277-11283 |
ISSN号 | 0022-3263 |
DOI | 10.1021/acs.joc.1c00307 |
通讯作者 | Yue, Jian-Min(jmyue@simm.ac.cn) |
英文摘要 | Two eudesmane-guaiane/lindenane heterocoupled sesquiterpenoid dimers, horienoids A (1) and B (2) with new carbon skeletons, from Hedyosmum orientale were characterized by a combined method. Compound 1 featured a unique 2,10-dioxabicyclo[6.2.1]-undecane core moiety with an anti-Bredt bridgehead double bond. Their biogenetic pathways were proposed to involve Diels-Alder and cascade rearrangement reactions as the key steps. Compound 2 exhibited a potent anti-inflammatory effect on LPS-induced BV-2 microglial cells. |
WOS关键词 | A-C ; CHLORANTHUS ; SPECTRA ; PLANTS |
资助项目 | National Natural Science Foundation of China[21772213] ; National Natural Science Foundation of China[81872758] ; National Natural Science Foundation of China[81872859] ; Shanghai Rising-Star program Foundation (SCST)[19QA1410800] ; Youth Innovation Promotion Association, CAS |
WOS研究方向 | Chemistry |
语种 | 英语 |
WOS记录号 | WOS:000687851300033 |
出版者 | AMER CHEMICAL SOC |
源URL | [http://119.78.100.183/handle/2S10ELR8/297664] ![]() |
专题 | 新药研究国家重点实验室 |
通讯作者 | Yue, Jian-Min |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 2.Zhejiang Univ, Coll Pharmaceut Sci, Inst Modern Chinese Med, Hangzhou 310058, Peoples R China 3.Wuyi Univ, Sch Biotechnol & Hlth Sci, Jiangmen 529020, Peoples R China 4.Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res, Shanghai 201203, Peoples R China |
推荐引用方式 GB/T 7714 | Fan, Yao-Yue,Gan, Li-She,Chen, Shi-Xin,et al. Horienoids A and B, Two Heterocoupled Sesquiterpenoid Dimers from Hedyosmum orientale[J]. JOURNAL OF ORGANIC CHEMISTRY,2021,86(16):11277-11283. |
APA | Fan, Yao-Yue,Gan, Li-She,Chen, Shi-Xin,Gong, Qi,Zhang, Hai-Yan,&Yue, Jian-Min.(2021).Horienoids A and B, Two Heterocoupled Sesquiterpenoid Dimers from Hedyosmum orientale.JOURNAL OF ORGANIC CHEMISTRY,86(16),11277-11283. |
MLA | Fan, Yao-Yue,et al."Horienoids A and B, Two Heterocoupled Sesquiterpenoid Dimers from Hedyosmum orientale".JOURNAL OF ORGANIC CHEMISTRY 86.16(2021):11277-11283. |
入库方式: OAI收割
来源:上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。