Quassinoids with Inhibitory Activities against Plant Fungal Pathogens from Picrasma javanica
文献类型：期刊论文
| 作者 | Chen, Jian-Jun1; Bai, Wei1; Lu, Yu-Bo1; Feng, Zi-Yun1; Gao, Kun1; Yue, Jian-Min1,2,3
|
| 刊名 | JOURNAL OF NATURAL PRODUCTS
 |
| 出版日期 | 2021-08-27 |
| 卷号 | 84期号:8页码:2111-2120 |
| ISSN号 | 0163-3864 |
| DOI | 10.1021/acs.jnatprod.1c00096 |
| 通讯作者 | Gao, Kun(npchem@lzu.edu.cn) ; Yue, Jian-Min(jmyue@simm.ac.cn) |
| 英文摘要 | A bioactivity-guided study on the leaves of Picrasma javanica led to the isolation of 19 quassinoids, including 13 new compounds. The structures of the new compounds were elucidated by a combination of spectroscopic data analysis, X-ray crystallography studies, and electronic circular dichroism (ECD) data interpretation. Compounds 1-7 are rare examples of quassinoids with a keto carbonyl group at C-12. The biological activities of 11 of the more abundant isolates were evaluated against five phytopathogenic fungi in vitro, and several of them including 6 and 15 showed moderate inhibitory effects that were comparative to those of the positive control, carbendazim. In addition, the preliminary structure-activity relationships (SARs) of these quassinoids were also investigated. |
| WOS关键词 | ANTIFUNGAL ACTIVITIES ; CONSTITUENTS ; GLUCOSIDES ; BARK |
| 资助项目 | National Natural Science Foundation of China[81973193] ; Natural Science Foundation of Gansu[20JR5RA279] ; Funda-mental Research Funds for the Central Universities[lzujbky2019-ct03] |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000692038100006 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/297774]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Gao, Kun; Yue, Jian-Min |
| 作者单位 | 1.Lanzhou Univ, State Key Lab Appl Organ Chem, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Jian-Jun,Bai, Wei,Lu, Yu-Bo,et al. Quassinoids with Inhibitory Activities against Plant Fungal Pathogens from Picrasma javanica[J]. JOURNAL OF NATURAL PRODUCTS,2021,84(8):2111-2120. |
| APA | Chen, Jian-Jun,Bai, Wei,Lu, Yu-Bo,Feng, Zi-Yun,Gao, Kun,&Yue, Jian-Min.(2021).Quassinoids with Inhibitory Activities against Plant Fungal Pathogens from Picrasma javanica.JOURNAL OF NATURAL PRODUCTS,84(8),2111-2120. |
| MLA | Chen, Jian-Jun,et al."Quassinoids with Inhibitory Activities against Plant Fungal Pathogens from Picrasma javanica".JOURNAL OF NATURAL PRODUCTS 84.8(2021):2111-2120. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。