Application of metabolomics for revealing the interventional effects of functional foods on metabolic diseases
文献类型：期刊论文
| 作者 | Fu, Jia1; Zhang, Le-Le1; Li, Wei1; Zhang, Yan1; Zhang, Yamei2,3; Liu, Fang4; Zou, Liang5 |
| 刊名 | FOOD CHEMISTRY
 |
| 出版日期 | 2022-01-15 |
| 卷号 | 367页码:14 |
| 关键词 | Functional foods Metabolomics Metabolites Metabolic diseases Food processing |
| ISSN号 | 0308-8146 |
| DOI | 10.1016/j.foodchem.2021.130697 |
| 通讯作者 | Liu, Fang(lf86614@126.com) ; Zou, Liang(zouliangcdu@126.com) |
| 英文摘要 | Metabolomics is an important branch of systems biology, which can detect changes in the body's metabolism before and after the intervention of functional foods, identify effective metabolites, and predict the interventional effects and the mechanism. This review summarizes the latest research outcomes regarding interventional effects of functional foods on metabolic diseases via metabolomics analysis. Since metabolomics approaches are powerful strategies for revealing the changes in bioactive compounds of functional foods during processing and storage, we also discussed the effects of these parameters on functional food metabolites using metabolomics approaches. To date, a number of endogenous metabolites related to the metabolic diseases after functional foods intervention have been discovered. Unfortunately, the mechanisms of metabolic disease-related molecules are still unclear and require further studies. The combination of metabolomics with other omics technologies could further promote its ability to fully understand the precise biological processes of functional food intervention on metabolic diseases. |
| WOS关键词 | HIGH-FAT DIET ; NF-KAPPA-B ; UNTARGETED METABOLOMICS ; AMPELOPSIS-GROSSEDENTATA ; COMPOSITIONAL CHANGES ; LIPID-ACCUMULATION ; OXIDATIVE STRESS ; GLYCEMIC CONTROL ; INDUCED OBESITY ; GANODERIC ACID |
| 资助项目 | Health and Family Planning Com-mission of Chengdu-Key Disciplines of Clinical Pharmacy |
| WOS研究方向 | Chemistry ; Food Science & Technology ; Nutrition & Dietetics |
| 语种 | 英语 |
| WOS记录号 | WOS:000696986400008 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/297903]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Liu, Fang; Zou, Liang |
| 作者单位 | 1.Chengdu Univ, Sch Basic Med Sci, Chengdu 610106, Peoples R China 2.Chengdu Univ, Clin Genet Lab, Affiliated Hosp, Chengdu 610081, Peoples R China 3.Chengdu Univ, Clin Med Coll, Chengdu 610081, Peoples R China 4.Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 5.Chengdu Univ, Sichuan Engn & Technol Res Ctr Coarse Cereal Indu, Sch Food & Biol Engn, Minist Agr & Rural Affairs,Key Lab Coarse Cereal, Chengdu 610106, Peoples R China |
| 推荐引用方式 GB/T 7714 | Fu, Jia,Zhang, Le-Le,Li, Wei,et al. Application of metabolomics for revealing the interventional effects of functional foods on metabolic diseases[J]. FOOD CHEMISTRY,2022,367:14. |
| APA | Fu, Jia.,Zhang, Le-Le.,Li, Wei.,Zhang, Yan.,Zhang, Yamei.,...&Zou, Liang.(2022).Application of metabolomics for revealing the interventional effects of functional foods on metabolic diseases.FOOD CHEMISTRY,367,14. |
| MLA | Fu, Jia,et al."Application of metabolomics for revealing the interventional effects of functional foods on metabolic diseases".FOOD CHEMISTRY 367(2022):14. |
入库方式： OAI收割
来源：上海药物研究所
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