A Graphene-Based Sensor Array for High-Precision and Adaptive Target Identification with Ensemble Aptamers
文献类型：期刊论文
| 作者 | Pei, H ; Li, J ; Lv, M（吕敏） ; Wang, JY（王靖琰） ; Gao, JM ; Lu, JX ; Li, YP（李勇平） ; Huang, Q（黄庆） ; Hu, J（胡钧） ; Fan, CH（樊春海） |
| 刊名 | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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| 出版日期 | 2012 |
| 卷号 | 134期号:33 |
| ISSN号 | 0002-7863 |
| 英文摘要 | In this work, we report a new concept of adaptive "ensemble aptamers" (ENSaptamers) that exploits the collective recognition abilities of a small set of rationally designed, nonspecific DNA sequences to identify molecular or cellular targets discriminatively. In contrast to in vitro selected aptamers, which possess specific "lock-and-key" recognition, ENSaptamers rely on pattern recognition that mimics natural olfactory or gustatory systems. Nanographene oxide was employed to provide a low-background and highly reproducible fluorescent assay system. We demonstrate that this platform provides a highly discriminative and adaptive tool for high precision identification of a wide range of targets for diagnostic and proteomic applications with a nearly unlimited supply of ENSaptamer receptors. |
| 语种 | 英语 |
| WOS记录号 | WOS:000307699000045 |
| 公开日期 | 2013-09-11 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/13074]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Pei, H,Li, J,Lv, M,et al. A Graphene-Based Sensor Array for High-Precision and Adaptive Target Identification with Ensemble Aptamers[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2012,134(33). |
| APA | Pei, H.,Li, J.,Lv, M.,Wang, JY.,Gao, JM.,...&Fan, CH.(2012).A Graphene-Based Sensor Array for High-Precision and Adaptive Target Identification with Ensemble Aptamers.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,134(33). |
| MLA | Pei, H,et al."A Graphene-Based Sensor Array for High-Precision and Adaptive Target Identification with Ensemble Aptamers".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 134.33(2012). |
入库方式： OAI收割
来源：上海应用物理研究所
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