Comparison of 16 mm OSU-Nag and COMS eye plaques
文献类型：期刊论文
| 作者 | Zhang, HL ; Davidorf, F ; Qi, YJ（漆玉金） |
| 刊名 | JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS
 |
| 出版日期 | 2012 |
| 卷号 | 13期号:3 |
| ISSN号 | 1526-9914 |
| 英文摘要 | OSU-NAG eye plaques use fewer sources than COMS-plaques of comparable size, and do not employ a Silastic seed carrier insert. Monte Carlo modeling was used to calculate 3D dose distributions for a 16 mm OSU-NAG eye plaque and a 16 mm COMS eye plaque loaded with either Iodine-125 or Cesium-131 brachytherapy sources. The OSU-NAG eye plaque was loaded with eight sources forming two squares, whereas the COMS eye plaque was loaded with thirteen sources approximating three isocentric circles. A spherical eyeball 24.6 mm in diameter and an ellipsoid-like tumor 6 mm in height and 12 mm in the major and minor axes were used to evaluate the doses delivered. To establish a fair comparison, a water seed carrier was used instead of the Silastic seed carrier designed for the traditional COMS eye plaque. Calculations were performed on the dose distributions along the eye plaque axis and the DVHs of the tumor, as well as the 3D distribution. Our results indicated that, to achieve a prescription dose of 85 Gy at 6 mm from the inner sclera edge for a six-day treatment, the OSU-NAG eye plaque will need 6.16 U/source and 6.82 U/source for I-125 and Cs-131, respectively. The COMS eye plaque will require 4.02 U/source and 4.43 U/source for the same source types. The dose profiles of the two types of eye plaques on their central axes are within 9% difference for all applicable distances. The OSU-NAG plaque delivers about 10% and 12% more dose than the COMS for I-125 and Cs-131 sources, respectively, at the inner sclera edge, but 6% and 3% less dose at the opposite retina. The DVHs of the tumor for two types of plaques were within 6% difference. In conclusion, the dosimetric quality of the OSU-NAG eye plaque used in eye plaque brachytherapy is comparable to the COMS eye plaque. |
| 语种 | 英语 |
| WOS记录号 | WOS:000304141400013 |
| 公开日期 | 2013-09-11 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/13106]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Zhang, HL,Davidorf, F,Qi, YJ. Comparison of 16 mm OSU-Nag and COMS eye plaques[J]. JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS,2012,13(3). |
| APA | Zhang, HL,Davidorf, F,&Qi, YJ.(2012).Comparison of 16 mm OSU-Nag and COMS eye plaques.JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS,13(3). |
| MLA | Zhang, HL,et al."Comparison of 16 mm OSU-Nag and COMS eye plaques".JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS 13.3(2012). |
入库方式： OAI收割
来源：上海应用物理研究所
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