An Improved Approach to Poly(Ester-Carbonate) Conjugates
文献类型:期刊论文
作者 | Mo GJ ; Yue J ; Ma PA ; Huang YB ; Chen XS ; Jing XB |
刊名 | journal of biomaterials science-polymer edition
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出版日期 | 2012 |
卷号 | 23期号:1-4页码:375-389 |
关键词 | RING-OPENING POLYMERIZATION 5-METHYL-5-BENZYLOXYCARBONYL-1 AMPHIPHILIC BLOCK-COPOLYMERS 3-DIOXAN-2-ONE CARBONATE BUILDING-BLOCKS CO-CYCLIC CARBONATE)S POLY(L-LACTIDE-CO-BETA-MALIC ACID) BIODEGRADABLE POLYMERS HYDROXYL-GROUPS BEARING POLYCARBONATES |
ISSN号 | 0920-5063 |
通讯作者 | jing xb |
中文摘要 | a novel poly(ester-carbonate) (p(la-co-npc)) with activated pendant carboxyl groups was synthesized by ring-opening polymerization of l-lactide (la) and 2-methyl-2-(4-nitrophenoxycarbonyl)-propylene carbonate (npc) with diethyl zinc (znet2) as catalyst. gpc and nmr studies confirmed the co-polymer structure. the pendant 4-nitrophenyl carboxylate groups can react with amino-containing molecules, such as 3,6,9-trioxa-1,11-undecanediamine, doxorubicin and chitosan under mild conditions. therefore, any amino-containing molecules of biomedical interests can be conjugated to p(la-co-npc) efficiently and easily. the biocompatibility of the co-polymer was tested using l929 cell line, indicating that p(la-co-npc) is a promising biomedical material. (c) koninklijke brill nv, leiden, 2012 |
收录类别 | SCI收录期刊论文 |
语种 | 英语 |
WOS记录号 | WOS:000297809800021 |
公开日期 | 2013-09-23 |
源URL | [http://ir.ciac.jl.cn/handle/322003/48781] ![]() |
专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
推荐引用方式 GB/T 7714 | Mo GJ,Yue J,Ma PA,et al. An Improved Approach to Poly(Ester-Carbonate) Conjugates[J]. journal of biomaterials science-polymer edition,2012,23(1-4):375-389. |
APA | Mo GJ,Yue J,Ma PA,Huang YB,Chen XS,&Jing XB.(2012).An Improved Approach to Poly(Ester-Carbonate) Conjugates.journal of biomaterials science-polymer edition,23(1-4),375-389. |
MLA | Mo GJ,et al."An Improved Approach to Poly(Ester-Carbonate) Conjugates".journal of biomaterials science-polymer edition 23.1-4(2012):375-389. |
入库方式: OAI收割
来源:长春应用化学研究所
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