Hollow structures as drug carriers: Recognition, response, and release
文献类型：期刊论文
| 作者 | Zhao, Decai1,2; Yang, Nailiang1,2; Xu, Lekai1,3,4; Du, Jiang3,4; Yang, Yang5,6; Wang, Dan1,2 |
| 刊名 | NANO RESEARCH
 |
| 出版日期 | 2021-07-08 |
| 页码 | 19 |
| 关键词 | hollow structure drug delivery system carriers spatiotemporal |
| ISSN号 | 1998-0124 |
| DOI | 10.1007/s12274-021-3595-5 |
| 英文摘要 | Hollow structures have demonstrated great potential in drug delivery owing to their privileged structure, such as high surface-to-volume ratio, low density, large cavities, and hierarchical pores. In this review, we provide a comprehensive overview of hollow structured materials applied in targeting recognition, smart response, and drug release, and we have addressed the possible chemical factors and reactions in these three processes. The advantages of hollow nanostructures are summarized as follows: hollow cavity contributes to large loading capacity; a tailored structure helps controllable drug release; variable compounds adapt to flexible application; surface modification facilitates smart responsive release. Especially, because the multiple physical barriers and chemical interactions can be induced by multishells, hollow multishelled structure is considered as a promising material with unique loading and releasing properties. Finally, we conclude this review with some perspectives on the future research and development of the hollow structures as drug carriers. |
| WOS关键词 | MESOPOROUS SILICA NANOPARTICLES ; METAL-ORGANIC FRAMEWORK ; IN-VITRO ; DELIVERY-SYSTEM ; TEMPLATING SYNTHESIS ; SUSTAINED-RELEASE ; ORGANOSILICA NANOCAPSULES ; SHELL NANOPARTICLES ; SEQUENTIAL RELEASE ; LOADING CAPACITY |
| 资助项目 | National Natural Science Foundation of China[21821005] ; National Natural Science Foundation of China[21820102002] ; National Natural Science Foundation of China[21971244] ; National Key R&D Program of China[2016YFB0600903] |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000671718700005 |
| 出版者 | TSINGHUA UNIV PRESS |
| 资助机构 | National Natural Science Foundation of China ; National Key R&D Program of China |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/49406]  |
| 专题 | 中国科学院过程工程研究所 |
| 通讯作者 | Yang, Nailiang; Yang, Yang; Wang, Dan |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Zhengzhou Univ, Sch Mat Sci & Engn, Green Catalysis Ctr, Zhengzhou 450001, Peoples R China 4.Zhengzhou Univ, Sch Mat Sci & Engn, Coll Chem, Zhengzhou 450001, Peoples R China 5.Tongji Univ, Shanghai Pulm Hosp, Sch Med, Dept Thorac Surg, Shanghai 200433, Peoples R China 6.Tongji Univ, Sch Mat Sci & Engn, Shanghai 201804, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Decai,Yang, Nailiang,Xu, Lekai,et al. Hollow structures as drug carriers: Recognition, response, and release[J]. NANO RESEARCH,2021:19. |
| APA | Zhao, Decai,Yang, Nailiang,Xu, Lekai,Du, Jiang,Yang, Yang,&Wang, Dan.(2021).Hollow structures as drug carriers: Recognition, response, and release.NANO RESEARCH,19. |
| MLA | Zhao, Decai,et al."Hollow structures as drug carriers: Recognition, response, and release".NANO RESEARCH (2021):19. |
入库方式： OAI收割
来源：过程工程研究所
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