Ionozyme: ionic liquids as solvent and stabilizer for efficient bioactivation of CO2
文献类型：期刊论文
| 作者 | Ji, Xiuling6; Xue, Yaju6; Li, Zhuang6; Liu, Yanrong3; Liu, Lei6; Busk, Peter Kamp2; Lange, Lene1; Huang, Yuhong4,5,6; Zhang, Suojiang5,6 |
| 刊名 | GREEN CHEMISTRY
 |
| 出版日期 | 2021-08-18 |
| 页码 | 11 |
| ISSN号 | 1463-9262 |
| DOI | 10.1039/d1gc02503a |
| 英文摘要 | The efficient bioactivation of CO2 provides an alternative new strategy for producing high value chemicals and fuels. Normally, in vitro activation of CO2 can be achieved by using formate dehydrogenase (FDH). However, the CO2 solubility and the activity of commercial FDHCb remain a tough challenge for the efficient bioactivation of CO2. Here, we report a new "ionozyme" strategy created by using ionic liquids (ILs) as a solvent and enzyme stabilizer, resulting in a 142.3-fold increase in CO2 conversion over FDHCb. The ionozyme (FDHPa-[CH][Pro]-[TMGH][PhO]) was first developed by combing a discovered novel FDHPa with an efficient synergistic ionic microenvironment. The remarkable performance of this ionozyme is attributed to forming key intermediates [CH][ProCOO] and [TMGH][PhOCOO], stabilizing the enzyme structure with increased solvation structure, and shortening the distance (3.9 angstrom) between NADH and CO2 to favor the hydride transfer by facilitating their relative orientation and forming new hydrogen bonds at the active sites. This bioactivation of CO2 by this specific ionozyme represents ideal starting points for the sustainable carbon cycle. |
| WOS关键词 | MULTI-ENZYMATIC CONVERSION ; FORMATE DEHYDROGENASE ; CARBON-DIOXIDE ; REDUCTION ; SYSTEM ; GREEN ; RESOLUTION ; MECHANISM ; METHANOL ; ENZYMES |
| 资助项目 | Dalian National Laboratory for Clean Energy (DNL) Cooperation Fund, CAS[DNL201909] ; Natural Science Foundation of Beijing[2204097] ; Innovation Academy for Green Manufacture, CAS[IAGM2020C19] ; CAS Pioneer Hundred Program |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics |
| 语种 | 英语 |
| 出版者 | ROYAL SOC CHEMISTRY |
| WOS记录号 | WOS:000687280400001 |
| 资助机构 | Dalian National Laboratory for Clean Energy (DNL) Cooperation Fund, CAS ; Natural Science Foundation of Beijing ; Innovation Academy for Green Manufacture, CAS ; CAS Pioneer Hundred Program |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/49919]  |
| 专题 | 中国科学院过程工程研究所 |
| 通讯作者 | Huang, Yuhong; Zhang, Suojiang |
| 作者单位 | 1.Bioecon Res & Advisory, DK-2500 Copenhagen, Valby, Denmark 2.Roskilde Univ, Dept Sci & Environm, Univ Vej 1, DK-4000 Roskilde, Denmark 3.Lulea Univ Technol, Div Energy Sci, Energy Engn, Lulea, Sweden 4.Chinese Acad Sci, Dalian Natl Lab Clean Energy, Dalian 116023, Peoples R China 5.Chinese Acad Sci, Innovat Acad Green Manufacture, Beijing 100190, Peoples R China 6.Chinese Acad Sci, Inst Proc Engn, Beijing Key Lab Ion Liquids Clean Proc, CAS Key Lab Green Proc & Engn,State Key Lab Multi, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ji, Xiuling,Xue, Yaju,Li, Zhuang,et al. Ionozyme: ionic liquids as solvent and stabilizer for efficient bioactivation of CO2[J]. GREEN CHEMISTRY,2021:11. |
| APA | Ji, Xiuling.,Xue, Yaju.,Li, Zhuang.,Liu, Yanrong.,Liu, Lei.,...&Zhang, Suojiang.(2021).Ionozyme: ionic liquids as solvent and stabilizer for efficient bioactivation of CO2.GREEN CHEMISTRY,11. |
| MLA | Ji, Xiuling,et al."Ionozyme: ionic liquids as solvent and stabilizer for efficient bioactivation of CO2".GREEN CHEMISTRY (2021):11. |
入库方式： OAI收割
来源：过程工程研究所
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