The genome of a subterrestrial nematode reveals adaptations to heat
文献类型：期刊论文
| 作者 | Weinstein, Deborah J1; Allen, Sarah E1; Lau, Maggie C Y3 ; Erasmus, Mariana5; Asalone, Kathryn C1; WaltersConte, Kathryn1; Deikus, Gintaras6; Sebra, Robert6; Borgonie, Gaetan7; van Heerden, Esta5
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| 刊名 | NATURE COMMUNICATIONS
 |
| 出版日期 | 2019 |
| 卷号 | 10期号:1 |
| ISSN号 | 2041-1723 |
| 其他题名 | The genome of a subterrestrial nematode reveals adaptations to heat |
| 英文摘要 | The nematode Halicephalobus mephisto was originally discovered inhabiting a deep terrestrial aquifer 1.3 km underground. H. mephisto can thrive under conditions of abiotic stress including heat and minimal oxygen, where it feeds on a community of both chemolithotrophic and heterotrophic prokaryotes in an unusual ecosystem isolated from the surface biosphere. Here we report the comprehensive genome and transcriptome of this organism, identifying a signature of adaptation: an expanded repertoire of 70 kilodalton heat-shock proteins (Hsp70) and avrRpt2 induced gene 1 (AIG1) proteins. The expanded Hsp70 genes are transcriptionally induced upon growth under heat stress, and we find that positive selection is detectable in several members of this family. We further show that AIG1 may have been acquired by horizontal gene transfer (HGT) from a rhizobial fungus. Over one-third of the genes of H. mephisto are novel, highlighting the divergence of this nematode from other sequenced organisms. This work sheds light on the genomic basis of heat tolerance in a complete subterrestrial eukaryotic genome. |
| 资助项目 | [Technology Innovation Agency (TIA), an agency of the Department of Science and Technology (DST)] ; [NSF] ; [NIH] ; [NASA DC Space Grant Consortium grant] |
| 语种 | 英语 |
| 源URL | [http://ir.idsse.ac.cn/handle/183446/8792]  |
| 专题 | 深海科学研究部_地外海洋系统研究室 |
| 作者单位 | 1.American University 2.Cornell University 3.Princeton University 4.Institute of Deep-Sea Science and Engineering, Chinese Academy of Sciences 5.University of the Free State 6.Icahn School of Medicine at Mount Sinai 7.Extreme Life Isyensya 8.North West University - South Africa |
| 推荐引用方式 GB/T 7714 | Weinstein, Deborah J,Allen, Sarah E,Lau, Maggie C Y,et al. The genome of a subterrestrial nematode reveals adaptations to heat[J]. NATURE COMMUNICATIONS,2019,10(1). |
| APA | Weinstein, Deborah J.,Allen, Sarah E.,Lau, Maggie C Y.,Erasmus, Mariana.,Asalone, Kathryn C.,...&Bracht, John R.(2019).The genome of a subterrestrial nematode reveals adaptations to heat.NATURE COMMUNICATIONS,10(1). |
| MLA | Weinstein, Deborah J,et al."The genome of a subterrestrial nematode reveals adaptations to heat".NATURE COMMUNICATIONS 10.1(2019). |
入库方式： OAI收割
来源：深海科学与工程研究所
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