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  2. 深海科学与工程研究所
  3. 中国科学院深海科学与工程研究所
  4. 深海科学研究部
  5. 深海生物学研究室
  6. 深海鱼类物种与基因组多样性的研究
Genome of the butterfly hillstream loach provides insights into adaptations to torrential mountain stream life

文献类型：期刊论文

作者Deng, Yu1,2; Meng, Minghui1; Fang, Jian1; Jiang, Haifeng1,2; Sun, Ning1,2; Lv, Wenqi1,2; Lei, Yi1,2; Wang, Cheng1,2; Bo, Jing2,3; Liu, Chun4
刊名MOLECULAR ECOLOGY RESOURCES
出版日期2021-05-12
页码14
关键词adaptation butterfly hillstream loach craniofacial skeletogenesis unculi
ISSN号1755-098X
DOI10.1111/1755-0998.13400
英文摘要Butterfly hillstream loach (Beaufortia kweichowensis), a benthic fish in the torrential mountain streams, possesses a totally flat ventrum, flattened craniofacial and body skeletons, and enlarged paired fins covered by substantially small keratinous structures. However, little is known about the genetic basis of these specialized morphological adaptations. Here we present a 448.52-Mb genome assembly with contig N50 length of 5.53 Mb by integrating Illumina short-read sequencing, Nanopore long-read sequencing and HiC-based chromatin map. Demographic history reconstruction of the butterfly hillstream loach reveals that the population dynamics is correlated with the different stages of uplifting of the Tibetan Plateau. Comparative genomic analysis finds evidence of six keratin genes in butterfly hillstream loach evolving under positive selection. Within these genes, two keratin genes exhibit species-specific and divergent amino acid changes, suggesting a role in the formation of the unculi. Additionally, a series of positively selected genes, rapid evolving genes, specific variant genes and expanded gene families are found, including genes related to Hedgehog, Notch and BMP pathways, which may be involved in craniofacial development. These findings may have important implications for understanding the genetic basis of phenotypic adaptation to torrential mountain stream life.
WOS关键词PHYLOGENETIC ANALYSIS ; GENE FAMILY ; EVOLUTION ; SEQUENCE ; HEDGEHOG ; ALIGNMENT ; BALITORIDAE ; PROGRAM ; CYPRINIFORMES ; DIVERGENCE
资助项目National Natural Science Foundation of China[31702016] ; National Natural Science Foundation of China[31972866] ; Strategic Priority Research Program of Chinese Academy of Sciences[XDB31040104] ; Youth Innovation Promotion Association ; Chinese Academy of Sciences
WOS研究方向Biochemistry & Molecular Biology ; Environmental Sciences & Ecology ; Evolutionary Biology
语种英语
WOS记录号WOS:000649249600001
出版者WILEY
资助机构National Natural Science Foundation of China ; Strategic Priority Research Program of Chinese Academy of Sciences ; Youth Innovation Promotion Association ; Chinese Academy of Sciences
源URL[http://ir.idsse.ac.cn/handle/183446/8630]  
专题深海科学研究部_深海生物学研究室_深海鱼类物种与基因组多样性的研究
通讯作者Wang, Ying; Yang, Liandong; He, Shunping
作者单位1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
3.Chinese Acad Sci, Inst Deep Sea Sci & Engn, Sanya, Peoples R China
4.BGI Shenzhen, BGI Genom, Shenzhen, Peoples R China
5.Jianghan Univ, Coll Life Sci, Hubei Engn Res Ctr Protect & Utilizat Special Bio, Wuhan, Peoples R China
6.Chinese Acad Sci, Ctr Excellence Anim Evolut & Genet, Kunming, Yunnan, Peoples R China
推荐引用方式
GB/T 7714		 Deng, Yu,Meng, Minghui,Fang, Jian,et al. Genome of the butterfly hillstream loach provides insights into adaptations to torrential mountain stream life[J]. MOLECULAR ECOLOGY RESOURCES,2021:14.
APA Deng, Yu.,Meng, Minghui.,Fang, Jian.,Jiang, Haifeng.,Sun, Ning.,...&He, Shunping.(2021).Genome of the butterfly hillstream loach provides insights into adaptations to torrential mountain stream life.MOLECULAR ECOLOGY RESOURCES,14.
MLA Deng, Yu,et al."Genome of the butterfly hillstream loach provides insights into adaptations to torrential mountain stream life".MOLECULAR ECOLOGY RESOURCES (2021):14.

入库方式： OAI收割

来源：深海科学与工程研究所

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