Nanosized HCA-coated borate bioactive glass with improved wound healing effects on rodent model
文献类型：期刊论文
| 作者 | Chen, Ruiguo7,8,9; Li, Qian3,8,9; Zhang, Qi4; Xu, Shuai8,9,10; Han, Jian8,9,10; Huang, Peiyan7,8,9; Yu, Zhiwu8,9 ; Jia, Daping1; Liu, Juanjuan8,9; Jia, Huiling8,9,10
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| 刊名 | CHEMICAL ENGINEERING JOURNAL
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| 出版日期 | 2021-12-15 |
| 卷号 | 426 |
| ISSN号 | 1385-8947 |
| 关键词 | Bioactive glass nano-HCA@BG Dynamic immersion Porous structure Wound healing |
| DOI | 10.1016/j.cej.2021.130299 |
| 通讯作者 | Zhang, Teng(teng_zhang@fzu.edu.cn) ; Ma, Kun(makun@hmfl.ac.cn) ; Wang, Junfeng(junfeng@hmfl.ac.cn) |
| 英文摘要 | Borate bioactive glass (BBG) stimulates angiogenesis and promotes cell growth. However, controlling the degradation rate of BBG and maintaining the critical concentration of bioactive ions suitable for cell promotion and differentiation remain great challenges in soft tissue repair. In this study, a novel approach was proposed to produce nanosized CO32- -containing hydroxyapatite (HCA)-coated BBG (nano-HCA@BG). Unlike the previously reported hard-to-degrade hydroxyapatite (HA) coating after static soaking treatment of BBG, the nano-HCA@BG, obtained by dynamically immersing the BBG powder in a flowing buffer, had a porous structure and was surfacecoated with a layer of amorphous HCA, which improved the biocompatibility and retained the biodegradability of BBG. The effects of nano-HCA@BG were evaluated and compared with those of powdered BBG at the cellular and animal levels. The formation of the HCA-coated nanoporous architecture significantly improves biocompatibility, promotes cell growth and proliferation, and is beneficial for wound healing in rodent skin defects. |
| WOS关键词 | CONTROLLABLE DEGRADATION ; COMPOSITE SCAFFOLDS ; SILICATE 45S5 ; BONE ; HYDROXYAPATITE ; CONVERSION ; CALCIUM ; RAMAN ; BOROSILICATE ; DISSOLUTION |
| 资助项目 | National Natural Science Foundation of China[U1732155] ; National Natural Science Foundation of China[3190110313] ; National Natural Science Foundation of China[U1632274] ; Ministry of Science and Technology of China[2016YFA0400901] ; Doctor Research Fund of Henan University of Technology[2019BS019] ; HighMagnetic Field Laboratory of Anhui Province |
| WOS研究方向 | Engineering |
| 语种 | 英语 |
| 出版者 | ELSEVIER SCIENCE SA |
| WOS记录号 | WOS:000722298200005 |
| 资助机构 | National Natural Science Foundation of China ; Ministry of Science and Technology of China ; Doctor Research Fund of Henan University of Technology ; HighMagnetic Field Laboratory of Anhui Province |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/126758]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Zhang, Teng; Ma, Kun; Wang, Junfeng |
| 作者单位 | 1.First Affiliated Hosp Anhui Med Univ, Dept Plast Surg, Hefei 230032, Anhui, Peoples R China 2.Univ Maryland, Dept Mat Sci & Engn, College Pk, MD 20742 USA 3.Henan Univ Technol, Sch Food Sci & Technol, Zhengzhou 450001, Henan, Peoples R China 4.Nanjing Vocat Univ Ind Technol, Sch Traff Engn, Nanjing 210046, Jiangsu, Peoples R China 5.East China Normal Univ, Sch Phys & Elect Sci, Shanghai Key Lab Magnet Resonance, Shanghai 200241, Peoples R China 6.Songshan Lake Mat Lab, Neutron Sci Platform, Dongguan 523808, Guangdong, Peoples R China 7.Fuzhou Univ, Coll Mat Sci & Engn, Fuzhou 350108, Fujian, Peoples R China 8.Hefei Inst Phys Sci Chinese Acad Sci, High Field Magnet Lab, CAS Key Lab High Magnet Field & Ion Beam Phys Bio, Hefei 230031, Anhui, Peoples R China 9.Chinese Acad Sci, Hefei, Anhui, Peoples R China 10.Univ Sci & Technol China, Hefei 230026, Anhui, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Ruiguo,Li, Qian,Zhang, Qi,et al. Nanosized HCA-coated borate bioactive glass with improved wound healing effects on rodent model[J]. CHEMICAL ENGINEERING JOURNAL,2021,426. |
| APA | Chen, Ruiguo.,Li, Qian.,Zhang, Qi.,Xu, Shuai.,Han, Jian.,...&Wang, Junfeng.(2021).Nanosized HCA-coated borate bioactive glass with improved wound healing effects on rodent model.CHEMICAL ENGINEERING JOURNAL,426. |
| MLA | Chen, Ruiguo,et al."Nanosized HCA-coated borate bioactive glass with improved wound healing effects on rodent model".CHEMICAL ENGINEERING JOURNAL 426(2021). |
入库方式： OAI收割
来源：合肥物质科学研究院
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