Hepatoid Adenocarcinoma of the Lung
文献类型：期刊论文
| 作者 | Li, Meihui1,2,3,4; Fan, Ying1,2,3,4; Lu, Hongyang1,2,3,4 |
| 刊名 | TECHNOLOGY IN CANCER RESEARCH & TREATMENT
 |
| 出版日期 | 2021-11-01 |
| 卷号 | 20 |
| 关键词 | hepatoid adenocarcinoma of the lung (HAL) alpha-fetoprotein (AFP) histopathological characteristics immunohistochemical staining treatment prognosis |
| ISSN号 | 1533-0346 |
| DOI | 10.1177/15330338211057983 |
| 通讯作者 | Lu, Hongyang(luhy@zjcc.org.cn) |
| 英文摘要 | Hepatoid adenocarcinoma of the lung (HAL) is an comparatively rare malignant tumor originating from the lung with shorter survival. HAL morphologically and pathologically exhibits hepatocellular carcinoma (HCC)-like characteristics, while its clinical features resemble pulmonary adenocarcinoma. High concentration of alpha-fetoprotein (AFP) is often detected in the serum of HAL patients with no hepatic occupying lesion. Patients with AFP-negative HAL survive a few months longer than those with positive AFP test. HAL is a rare type of carcinoma, so there is a lack of systematic and extensive statistical research. The treatment strategy for HAL is similar to common lung adenocarcinoma. Complete surgical resection and adjuvant chemotherapy are the current major treatments for HAL patients. There are also a few of case reports suggesting that HAL patients may benefit from immunotherapy and targeted therapy. This review focuses on the clinical and pathological features, immunohistochemical staining characteristics, treatment and prognosis of HAL. |
| WOS关键词 | ALPHA-FETOPROTEIN ; GASTRIC-CARCINOMA ; METASTASIS ; FEATURES ; THERAPY ; CANCER |
| 资助项目 | Zhejiang Province Medical Science and Technology Project[2020ZH001] |
| WOS研究方向 | Oncology |
| 语种 | 英语 |
| WOS记录号 | WOS:000726626500001 |
| 出版者 | SAGE PUBLICATIONS INC |
| 资助机构 | Zhejiang Province Medical Science and Technology Project |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/126776]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Lu, Hongyang |
| 作者单位 | 1.Univ Chinese Acad Sci, Zhejiang Key Lab Diag & Treatment Technol Thorac, Canc Hosp, Zhejiang Canc Hosp, Beijing 310022, Peoples R China 2.Chinese Acad Sci, Inst Basic Med & Canc IBMC, Beijing 310022, Peoples R China 3.Wenzhou Med Univ, Clin Med Coll 1, Wenzhou, Peoples R China 4.Univ Chinese Acad Sci, Dept Thorac Med Oncol, Zhejiang Canc Hosp, Canc Hosp, Beijing 310022, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Meihui,Fan, Ying,Lu, Hongyang. Hepatoid Adenocarcinoma of the Lung[J]. TECHNOLOGY IN CANCER RESEARCH & TREATMENT,2021,20. |
| APA | Li, Meihui,Fan, Ying,&Lu, Hongyang.(2021).Hepatoid Adenocarcinoma of the Lung.TECHNOLOGY IN CANCER RESEARCH & TREATMENT,20. |
| MLA | Li, Meihui,et al."Hepatoid Adenocarcinoma of the Lung".TECHNOLOGY IN CANCER RESEARCH & TREATMENT 20(2021). |
入库方式： OAI收割
来源：合肥物质科学研究院
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