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Weighted Gene Co-expression Network Analysis (WGCNA) Reveals the Hub Role of Protein Ubiquitination in the Acquisition of Desiccation Tolerance in Boea hygrometrica

文献类型：期刊论文

作者Lin, Chih-Ta; Xu, Tao; Xing, Shi-Lai; Zhao, Li; Sun, Run-Ze; Liu, Yang3; Moore, John Paul1; Deng, Xin3
刊名PLANT AND CELL PHYSIOLOGY
出版日期2019
卷号60期号:12页码:2707-2719
关键词Boea hygrometrica Protein ubiquitination Resurrection plant Transcription repressor VAL1 WGCNA
ISSN号0032-0781
DOI10.1093/pcp/pcz160
文献子类Article
英文摘要Boea hygrometrica can survive extreme drought conditions and has been used as a model to study desiccation tolerance. A genome-wide transcriptome analysis of B. hygrometrica showed that the plant can survive rapid air-drying after experiencing a slow soil-drying acclimation phase. In addition, a weighted gene co-expression network analysis was used to study the transcriptomic datasets. A network comprising 22 modules was constructed, and seven modules were found to be significantly related to desiccation response using an enrichment analysis. Protein ubiquitination was observed to be a common process linked to hub genes in all the seven modules. Ubiquitin-modified proteins with diversified functions were identified using immunoprecipitation coupled with mass spectrometry. The lowest level of ubiquitination was noted at the full soil drying priming stage, which coincided the accumulation of dehydration-responsive gene BhLEA2. The highly conserved RY motif (CAT GCA) was identified from the promoters of ubiquitin-related genes that were downregulated in the desiccated samples. An in silico gene expression analysis showed that the negative regulation of ubiquitin-related genes is potentially mediated via a B3 domain-containing transcription repressor VAL1. This study suggests that priming may involve the transcriptional regulation of several major processes, and the transcriptional regulation of genes in protein ubiquitination may play a hub role to deliver acclimation signals to posttranslational level in the acquisition of desiccation tolerance in B. hygrometrica.
学科主题Plant Sciences ; Cell Biology
出版地OXFORD
电子版国际标准刊号1471-9053
WOS关键词PLANT-CELL-WALLS ; RESURRECTION PLANT ; TORTULA-RURALIS ; TRANSCRIPTIONAL REPRESSOR ; STRESS ; DEHYDRATION ; EXPRESSION ; LIGASE ; ACCUMULATION ; INVOLVEMENT
WOS研究方向Plant Sciences ; Cell Biology
语种英语
WOS记录号WOS:000504924100011
出版者OXFORD UNIV PRESS
资助机构National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31270312, 31770293, 31470361] ; Chinese Academy of Sciences Taiwan Young Talent Programme [2016TW2SA0001] ; South Africa-China Bilateral Grant ; National Research Foundation (South Africa)National Research Foundation - South Africa [88484] ; Ministry of Science and Technology (China)Ministry of Science and Technology, China [2003-256-9]
源URL[http://ir.ibcas.ac.cn/handle/2S10CLM1/19713]  
专题中科院北方资源植物重点实验室
作者单位1.Chinese Acad Sci, Inst Bot, Beijing Bot Garden, Beijing 100093, Peoples R China
2.Stellenbosch Univ, Inst Wine Biotechnol, Dept Viticulture & Oenol, ZA-7602 Matieland, South Africa
3.Chinese Acad Sci, Inst Bot, Key Lab Plant Resources, Beijing 100093, Peoples R China
推荐引用方式
GB/T 7714		 Lin, Chih-Ta,Xu, Tao,Xing, Shi-Lai,et al. Weighted Gene Co-expression Network Analysis (WGCNA) Reveals the Hub Role of Protein Ubiquitination in the Acquisition of Desiccation Tolerance in Boea hygrometrica[J]. PLANT AND CELL PHYSIOLOGY,2019,60(12):2707-2719.
APA Lin, Chih-Ta.,Xu, Tao.,Xing, Shi-Lai.,Zhao, Li.,Sun, Run-Ze.,...&Deng, Xin.(2019).Weighted Gene Co-expression Network Analysis (WGCNA) Reveals the Hub Role of Protein Ubiquitination in the Acquisition of Desiccation Tolerance in Boea hygrometrica.PLANT AND CELL PHYSIOLOGY,60(12),2707-2719.
MLA Lin, Chih-Ta,et al."Weighted Gene Co-expression Network Analysis (WGCNA) Reveals the Hub Role of Protein Ubiquitination in the Acquisition of Desiccation Tolerance in Boea hygrometrica".PLANT AND CELL PHYSIOLOGY 60.12(2019):2707-2719.

入库方式： OAI收割

来源：植物研究所

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