Transposable elements drive rapid phenotypic variation in Capsella rubella
文献类型：期刊论文
| 作者 | Niu, Xiao-Min; Xu, Yong-Chao; Li, Zi-Wen; Bian, Yu-Tao; Hou, Xing-Hui; Chen, Jia-Fu; Zou, Yu-Pan; Jiang, Juan; Wu, Qiong; Ge, Song
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| 刊名 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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| 出版日期 | 2019 |
| 卷号 | 116期号:14页码:6908-6913 |
| 关键词 | Brassicaceae Capsella rubella natural variation rapid phenotypic variation transposable elements |
| ISSN号 | 0027-8424 |
| DOI | 10.1073/pnas.1811498116 |
| 文献子类 | Article |
| 英文摘要 | Rapid phenotypic changes in traits of adaptive significance are crucial for organisms to thrive in changing environments. How such phenotypic variation is achieved rapidly, despite limited genetic variation in species that experience a genetic bottleneck is unknown. Capsella rubella, an annual and inbreeding forb (Brassicaceae), is a great system for studying this basic question. Its distribution is wider than those of its congeneric species, despite an extreme genetic bottleneck event that severely diminished its genetic variation. Here, we demonstrate that transposable elements (TEs) are an important source of genetic variation that could account for its high phenotypic diversity. TEs are (i) highly enriched in C. rubella compared with its outcrossing sister species Capsella grandiflora, and (ii) 4.2% of polymorphic TEs in C. rubella are associated with variation in the expression levels of their adjacent genes. Furthermore, we show that frequent TE insertions at FLOWERING LOCUS C (FLC) in natural populations of C. rubella could explain 12.5% of the natural variation in flowering time, a key life history trait correlated with fitness and adaptation. In particular, we show that a recent TE insertion at the 3' UTR of FLC affects mRNA stability, which results in reducing its steady-state expression levels, to promote the onset of flowering. Our results highlight that TE insertions can drive rapid phenotypic variation, which could potentially help with adaptation to changing environments in a species with limited standing genetic variation. |
| 学科主题 | Multidisciplinary Sciences |
| 出版地 | WASHINGTON |
| WOS关键词 | ARABIDOPSIS-THALIANA ; GENETIC PARADOX ; RECENT SPECIATION ; FLOWERING-TIME ; ADAPTATION ; EVOLUTION ; MUTATION ; IDENTIFICATION ; CONSEQUENCES ; EXPRESSION |
| WOS研究方向 | Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:000463069900067 |
| 出版者 | NATL ACAD SCIENCES |
| 资助机构 | National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [91731306] ; Strategic Priority Research Program of the Chinese Academy of SciencesChinese Academy of Sciences [XDB27010305] ; Innovative Academy of Seed Design, Chinese Academy of Sciences ; Chinese Academy of Sciences President's International Fellowship for Visiting Scientists ; Monash University Larkins Fellowship |
| 源URL | [http://ir.ibcas.ac.cn/handle/2S10CLM1/19750]  |
| 专题 | 植物研究所_系统与进化植物学研究中心_系统与进化植物学研究中心_学位论文 |
| 作者单位 | 1.Chinese Acad Sci, Inst Bot, State Key Lab Systemat & Evolutionary Bot, Beijing 100093, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Monash Univ, Sch Biol Sci, Clayton, Vic 3800, Australia |
| 推荐引用方式 GB/T 7714 | Niu, Xiao-Min,Xu, Yong-Chao,Li, Zi-Wen,et al. Transposable elements drive rapid phenotypic variation in Capsella rubella[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2019,116(14):6908-6913. |
| APA | Niu, Xiao-Min.,Xu, Yong-Chao.,Li, Zi-Wen.,Bian, Yu-Tao.,Hou, Xing-Hui.,...&Guo, Ya-Long.(2019).Transposable elements drive rapid phenotypic variation in Capsella rubella.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,116(14),6908-6913. |
| MLA | Niu, Xiao-Min,et al."Transposable elements drive rapid phenotypic variation in Capsella rubella".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116.14(2019):6908-6913. |
入库方式： OAI收割
来源：植物研究所
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