中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 心理研究所
  3. 中国科学院心理研究所
  4. 中国科学院心理健康重点实验室
The prevalence and clinical characteristics of diabetes mellitus in Chinese inpatients with chronic schizophrenia: a multicenter cross-sectional study

文献类型：期刊论文

作者Wang, Yanni1; Zeng, Lingyun6; Chen, Lijuan5; Zhou, Xin4; Huo, Lijuan3; Wang, Tingwei1; Zhou, Yongjie6; Zhang, Xiangyang2
刊名PEERJ
出版日期2021-11-30
卷号9页码:12
关键词Schizophrenia Diabetes mellitus Prevalence China Clinical characteristics
ISSN号2167-8359
DOI10.7717/peerj.12553
通讯作者Zhou, Yongjie(qingzhu1108@126.com) ; Zhang, Xiangyang(zhangxy@psych.ac.cn)
英文摘要Background. Diabetes mellitus (DM) is common among patients with schizophrenia. However, information on patients comorbid DM and schizophrenia is limited in China. The present study investigated the prevalence of DM and its clinical characteristics in Chinese inpatients with chronic schizophrenia. Methods. A cross-sectional study was performed in Chinese inpatients with chronic schizophrenia. Diagnosis of Diabetes was established using World Health Organization diagnostic criteria for diabetes mellitus (persistent fasting glucose levels >= 126 mg/dl or 2-h plasma glucose >= 200 mg/dL after a 75-g Oral Glucose Tolerance Test). Patients were also measured height, weight, waist circumference, hip circumference, triglyceride level, and cholesterol level. Patients' psychiatric symptoms were measured by the Positive and Negative Syndrome Scale (PANSS). Binary logistic regression analysis was performed to examine the associated demographic and clinical variables in chronic schizophrenia. Results. A total of 988 inpatients (64.6% male, average age of 47.19 +/- 12.55) was recruited. The prevalence of DM in Chinese patients with chronic schizophrenia was 13.8% (95% CI [11.6-15.9]%). Logistic regression analysis showed that overweight (OR = 1.90, 95% CI [1.20-3.03], p = 0.006), obesity (OR = 1.85, 95% CI [1.07-3.21], p = 0.028), comorbid hypertension (OR = 2.14, 95% CI [1.34-3.42], p = 0.002), and course of schizophrenia (OR = 1.03, 95% CI [1.01-1.06], p = 0.040) were significantly associated with the DM risk in patients with schizophrenia. Conclusion. The findings indicated that diabetes mellitus was non-negligible in patients with chronic schizophrenia. Patients with schizophrenia should be regularly monitored for DM. Overweight/obesity, long duration of schizophrenia, and comorbid hypertension possibly were risk factors for diabetes.
收录类别SCI
WOS关键词MAJOR DEPRESSIVE DISORDER ; METABOLIC SYNDROME ; RISK-FACTORS ; BIPOLAR DISORDER ; MENTAL-ILLNESS ; PEOPLE ; PREDICTORS ; MORTALITY
资助项目Sanming Project of Medicine in Shenzhen
WOS研究方向Science & Technology - Other Topics
语种英语
WOS记录号WOS:000728904900004
出版者PEERJ INC
资助机构Sanming Project of Medicine in Shenzhen
源URL[http://ir.psych.ac.cn/handle/311026/41392]  
专题心理研究所_中国科学院心理健康重点实验室
通讯作者Zhou, Yongjie; Zhang, Xiangyang
作者单位1.Sch Publ Hlth, Dept Maternal Child & Adolescent Hlth, Lanzhou, Peoples R China
2.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China
3.Guangzhou Med Univ, Affiliated Brain Hosp, Dept Psychiat, Guangzhou, Peoples R China
4.China Univ Geosci, Res Ctr Psychol & Hlth Sci, Wuhan, Peoples R China
5.South Cent Univ Nationalities, Sch Literature Journalism & Commun, Wuhan, Peoples R China
6.Shenzhen Kangning Hosp, Dept Psychiat Rehabil, Shenzhen, Peoples R China
推荐引用方式
GB/T 7714		 Wang, Yanni,Zeng, Lingyun,Chen, Lijuan,et al. The prevalence and clinical characteristics of diabetes mellitus in Chinese inpatients with chronic schizophrenia: a multicenter cross-sectional study[J]. PEERJ,2021,9:12.
APA Wang, Yanni.,Zeng, Lingyun.,Chen, Lijuan.,Zhou, Xin.,Huo, Lijuan.,...&Zhang, Xiangyang.(2021).The prevalence and clinical characteristics of diabetes mellitus in Chinese inpatients with chronic schizophrenia: a multicenter cross-sectional study.PEERJ,9,12.
MLA Wang, Yanni,et al."The prevalence and clinical characteristics of diabetes mellitus in Chinese inpatients with chronic schizophrenia: a multicenter cross-sectional study".PEERJ 9(2021):12.

入库方式： OAI收割

来源：心理研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。