Charting the human amygdala development across childhood and adolescence: Manual and automatic segmentation
文献类型：期刊论文
| 作者 | Zhou, Quan6,7; Liu, Siman6,7; Jiang, Chao5; He, Ye4; Zuo, Xi-Nian1,2,3,6,7
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| 刊名 | DEVELOPMENTAL COGNITIVE NEUROSCIENCE
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| 出版日期 | 2021-12-01 |
| 卷号 | 52页码:16 |
| 关键词 | Amygdala Brain development Growth chart MRI Reliability |
| ISSN号 | 1878-9293 |
| DOI | 10.1016/j.dcn.2021.101028 |
| 通讯作者 | Zuo, Xi-Nian(xinian.zuo@bnu.edu.cn) |
| 英文摘要 | The developmental pattern of the amygdala throughout childhood and adolescence has been inconsistently reported in previous neuroimaging studies. Given the relatively small size of the amygdala on full brain MRI scans, discrepancies may be partly due to methodological differences in amygdalar segmentation. To investigate the impact of volume extraction methods on amygdala volume, we compared FreeSurfer, FSL and volBrain segmentation measurements with those obtained by manual tracing. The manual tracing method, which we used as the 'gold standard', exhibited almost perfect intra-and inter-rater reliability. We observed systematic differences in amygdala volumes between automatic (FreeSurfer and volBrain) and manual methods. Specifically, compared with the manual tracing, FreeSurfer estimated larger amygdalae, and volBrain produced smaller amygdalae while FSL demonstrated a mixed pattern. The tracing bias was not uniform, but higher for smaller amygdalae. We further modeled amygdalar growth curves using accelerated longitudinal cohort data from the Chinese Color Nest Project (http://deepneuro.bnu.edu.cn/?p=163). Trajectory modeling and statistical assessments of the manually traced amygdalae revealed linearly increasing and parallel developmental patterns for both girls and boys, although the amygdalae of boys were larger than those of girls. Compared to these trajectories, the shapes of developmental curves were similar when using the volBrain derived volumes. FreeSurfer derived trajectories had more nonlinearities and appeared flatter. FSL derived trajectories demonstrated an inverted U shape and were significantly different from those derived from manual tracing method. The use of amygdala volumes adjusted for total gray-matter volumes, but not intracranial volumes, resolved the shape discrepancies and led to reproducible growth curves between manual tracing and the automatic methods (except FSL). Our findings revealed steady growth of the human amygdala, mirroring its functional development across the school age. Methodological improvements are warranted for current automatic tools to achieve more accurate amygdala structure at school age, calling for next generation tools. |
| 收录类别 | SCI |
| WOS关键词 | HIPPOCAMPAL VOLUME ; BRAIN-DEVELOPMENT ; LIFE-SPAN ; MISWIRED CONNECTOME ; NORMATIVE MODELS ; GRAY-MATTER ; CHILDREN ; ANXIETY ; AUTISM ; GROWTH |
| 资助项目 | Key-Area Research and Development Program of Guangdong Province, China[2019B030335001] ; Start-up Funds for Leading Talents at Beijing Normal University ; National Basic Science Data Center Chinese Data-sharing Warehouse for In-vivo Imaging Brain''[NBSDC-DB-15] ; Beijing Municipal Science and Technology Commission, China[Z161100002616023] ; Beijing Municipal Science and Technology Commission, China[Z181100001518003] ; CAS-NWO Programme[153111KYSB20160020] ; National Natural Science Foundation of China[81220108014] ; Guangxi BaGui Scholarship, China[201621] ; National Basic Research (973) Program, China[2015CB351702] |
| WOS研究方向 | Psychology ; Neurosciences & Neurology |
| 语种 | 英语 |
| WOS记录号 | WOS:000718382600001 |
| 出版者 | ELSEVIER SCI LTD |
| 资助机构 | Key-Area Research and Development Program of Guangdong Province, China ; Start-up Funds for Leading Talents at Beijing Normal University ; National Basic Science Data Center Chinese Data-sharing Warehouse for In-vivo Imaging Brain'' ; Beijing Municipal Science and Technology Commission, China ; CAS-NWO Programme ; National Natural Science Foundation of China ; Guangxi BaGui Scholarship, China ; National Basic Research (973) Program, China |
| 源URL | [http://ir.psych.ac.cn/handle/311026/41230]  |
| 专题 | 心理研究所_认知与发展心理学研究室 |
| 通讯作者 | Zuo, Xi-Nian |
| 作者单位 | 1.Beijing Normal Univ, State Key Lab Cognit Neurosci & Learning, Beijing 100875, Peoples R China 2.Beijing Normal Univ, Dev Populat Neurosci Res Ctr, IDG McGovern Inst Brain Res, Beijing 100875, Peoples R China 3.Natl Basic Sci Data Ctr, Beijing 100190, Peoples R China 4.Beijing Univ Posts & Telecommun, Sch Artificial Intelligence, Beijing 100876, Peoples R China 5.Capital Normal Univ, Sch Psychol, Beijing 100048, Peoples R China 6.Univ Chinese Acad Sci, Dept Psychol, Beijing 100049, Peoples R China 7.Chinese Acad Sci, Inst Psychol, Beijing 100101, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, Quan,Liu, Siman,Jiang, Chao,et al. Charting the human amygdala development across childhood and adolescence: Manual and automatic segmentation[J]. DEVELOPMENTAL COGNITIVE NEUROSCIENCE,2021,52:16. |
| APA | Zhou, Quan,Liu, Siman,Jiang, Chao,He, Ye,&Zuo, Xi-Nian.(2021).Charting the human amygdala development across childhood and adolescence: Manual and automatic segmentation.DEVELOPMENTAL COGNITIVE NEUROSCIENCE,52,16. |
| MLA | Zhou, Quan,et al."Charting the human amygdala development across childhood and adolescence: Manual and automatic segmentation".DEVELOPMENTAL COGNITIVE NEUROSCIENCE 52(2021):16. |
入库方式： OAI收割
来源：心理研究所
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