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Altered Neural Processing of Reward and Punishment in Women With Methamphetamine Use Disorder

文献类型：期刊论文

作者Wei, Shuguang8; Xue, Zhaoxia7; Sun, Wujun6; Han, Jie5; Wu, Haiyan1,2; Liu, Xun3,4
刊名FRONTIERS IN PSYCHIATRY
出版日期2021-10-13
卷号12页码:15
关键词methamphetamine (MA) use disorder reward processing punishment processing Cue-P3 stimulus-preceding negativity (SPN) feedback-related negativity (FRN) feedback P3 (FB-P3)
ISSN号1664-0640
DOI10.3389/fpsyt.2021.692266
通讯作者Wu, Haiyan(haiyanwu@um.edu.mo) ; Liu, Xun(liux@psych.ac.cn)
英文摘要It has been suggested that the altered function of reward and punishment is an important vulnerability factor leading to the development of drug use disorders. Previous studies have identified evidence of neurophysiological dysfunction in the reward process of individuals with substance use disorders. To date, only a few event-related potential (ERP) studies have examined the neural basis of reward and punishment processing in women with methamphetamine (MA) use disorders. The current ERP research aims to investigate the neurophysiological mechanisms of reward and punishment in women with MA use disorder using a monetary incentive delay task. Nineteen women with MA use disorder (MA group) and 20 healthy controls (HC group) were recruited in this study. The behavioral data showed that the reaction time (RT) was faster and the response accuracy (ACC) was higher for the potential reward and punishment conditions compared to neutral conditions. During the monetary incentive anticipation stage, the Cue-P3, and stimulus-preceding negativity (SPN) were larger in the MA group than in the HC group. The SPN under the potential reward condition was larger than that under the neutral condition in the MA group but not in the HC group. During the monetary incentive consummation stage, the feedback-related negativity and feedback P3 (FB-P3) following positive feedback were significantly larger than negative feedback in the potential reward condition for the HC group, but not for the MA group. However, the FB-P3 following negative feedback was significantly larger than positive feedback in the potential punishment condition for the MA group, but not the HC group. The results suggest that women with MUD have stronger expectations of generic reward and stronger response of generic harm avoidance, which could be targeted in designing interventions for women with MA use disorder.

收录类别SCI
WOS关键词INCENTIVE-SENSITIZATION ; MONETARY REWARD ; TEMPORAL DYNAMICS ; DECISION-MAKING ; ADDICTION ; SENSITIVITY ; ACTIVATION ; PREDICTION ; VALENCE ; FMRI
资助项目National Key R&D Program of China[2016YFC0800901-Z03] ; National Social Science Foundation of China[18BSH128] ; Natural Science Foundation of Guangdong Province[2021A1515012509]
WOS研究方向Psychiatry
语种英语
WOS记录号WOS:000713250900001
出版者FRONTIERS MEDIA SA
资助机构National Key R&D Program of China ; National Social Science Foundation of China ; Natural Science Foundation of Guangdong Province
源URL[http://ir.psych.ac.cn/handle/311026/41085]  
专题心理研究所_中国科学院行为科学重点实验室
通讯作者Wu, Haiyan; Liu, Xun
作者单位1.Univ Macau, Ctr Cognit & Brain Sci, Macau, Peoples R China
2.Univ Macau, Dept Psychol, Macau, Peoples R China
3.Chinese Acad Sci, Inst Psychol, Key Lab Behav Sci, Beijing, Peoples R China
4.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
5.Hebei Female Drug Rehabil Ctr, Shijiazhuang, Peoples R China
6.Henan Normal Univ, Fac Educ, Xinxiang, Peoples R China
7.Shanxi Med Univ, Coll Humanities & Social Sci, Dept Appl Psychol, Taiyuan, Peoples R China
8.Hebei Normal Univ, Coll Educ, Dept Psychol, Shijiazhuang, Peoples R China
推荐引用方式
GB/T 7714		 Wei, Shuguang,Xue, Zhaoxia,Sun, Wujun,et al. Altered Neural Processing of Reward and Punishment in Women With Methamphetamine Use Disorder[J]. FRONTIERS IN PSYCHIATRY,2021,12:15.
APA Wei, Shuguang,Xue, Zhaoxia,Sun, Wujun,Han, Jie,Wu, Haiyan,&Liu, Xun.(2021).Altered Neural Processing of Reward and Punishment in Women With Methamphetamine Use Disorder.FRONTIERS IN PSYCHIATRY,12,15.
MLA Wei, Shuguang,et al."Altered Neural Processing of Reward and Punishment in Women With Methamphetamine Use Disorder".FRONTIERS IN PSYCHIATRY 12(2021):15.

入库方式： OAI收割

来源：心理研究所

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