Cristatumins A-D, new indole alkaloids from the marine-derived endophytic fungus Eurotium cristatum EN-220
文献类型：期刊论文
| 作者 | Du, Feng-Yu1,2; Li, Xiao-Ming1; Li, Chun-Shun1; Shang, Zhuo1; Wang, Bin-Gui1
|
| 刊名 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
 |
| 出版日期 | 2012-07-15 |
| 卷号 | 22期号:14页码:4650-4653 |
| ISSN号 | 0960-894X |
| 关键词 | Marine endophyte Eurotium cristatum Indole alkaloid Antimicrobial activity Brine shrimp inhibition |
| 通讯作者 | Wang, BG (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China. |
| 英文摘要 | Four new indole alkaloids, namely, cristatumins A-D (1-4), along with six known congeners (5-10) were identified from the culture extract of Eurotium cristatum EN-220, an endophytic fungus isolated from the marine alga Sargassum thunbergii. The structures of these compounds were established on the basis of extensive spectroscopic analysis. Each of these compounds was evaluated for antimicrobial and insecticidal activity. Compounds 1 and 9 showed antibacterial activity against Escherichia coli and Staphyloccocus aureus, respectively, while compounds 2, 6, and 7 exhibited moderate lethal activity against brine shrimp. Preliminary structure-activity relationships were also discussed. (C) 2012 Elsevier Ltd. All rights reserved. |
| 学科主题 | Chemistry, Medicinal ; Chemistry, Organic |
| 收录类别 | SCI |
| 原文出处 | 10.1016/j.bmcl.2012.05.088 |
| 语种 | 英语 |
| WOS记录号 | WOS:000306101300030 |
| 公开日期 | 2013-09-24 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/12307]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Du, Feng-Yu,Li, Xiao-Ming,Li, Chun-Shun,et al. Cristatumins A-D, new indole alkaloids from the marine-derived endophytic fungus Eurotium cristatum EN-220[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2012,22(14):4650-4653. |
| APA | Du, Feng-Yu,Li, Xiao-Ming,Li, Chun-Shun,Shang, Zhuo,&Wang, Bin-Gui.(2012).Cristatumins A-D, new indole alkaloids from the marine-derived endophytic fungus Eurotium cristatum EN-220.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,22(14),4650-4653. |
| MLA | Du, Feng-Yu,et al."Cristatumins A-D, new indole alkaloids from the marine-derived endophytic fungus Eurotium cristatum EN-220".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 22.14(2012):4650-4653. |
入库方式： OAI收割
来源：海洋研究所
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