Expression profiles of antimicrobial peptides (AMPs) and their regulation by Relish
文献类型：期刊论文
| 作者 | Wang Dongdong1,2; Li Fuhua1; Li Shihao1,2; Wen Rong1,2; Xiang Jianhai1
|
| 刊名 | CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
 |
| 出版日期 | 2012-07-01 |
| 卷号 | 30期号:4页码:611-619 |
| 关键词 | antimicrobial peptides (AMPs) expression profiles bacteria Relish RNA interference |
| ISSN号 | 0254-4059 |
| 通讯作者 | Li, FH (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China. |
| 英文摘要 | Antimicrobial peptides (AMPs), as key immune effectors, play important roles in the innate immune system of invertebrates. Different types of AMPs, including Penaeidin, Crustin, ALF (antilipopolysaccharide factor) have been identified in different penaeid shrimp; however, systematic analyses on the function of different AMPs in shrimp responsive to different types of bacteria are very limited. In this study, we analyzed the expression profiles of AMPs in the Chinese shrimps, Fenneropenaeus chinensis, simultaneously by real-time RT-PCR (reverse transcription-polymerase chain reaction) when shrimp were challenged with Micrococcus lysodeikticus (Gram-positive, G(+)) or Vibrio anguillarium (Gram-negative, G(-)). Different AMPs showed different expression profiles when shrimp were injected with one type of bacterium, and one AMP also showed different expression profiles when shrimp were challenged with different bacteria. Furthermore, the expression of these AMPs showed temporal expression profiles, suggesting that different AMPs function coordinately in bacteria-infected shrimp. An RNA interference approach was used to study the function of the Relish transcription factor in regulating the transcription of different AMPs. The current study showed that Relish could regulate the transcription of different AMPs in shrimp. Differential expression profiles of AMPs in shrimp injected with different types of bacteria indicated that a complicated antimicrobial response network existed in shrimp. These data contribute to our understanding of immunity in shrimp and may provide a strategy for the control of disease in shrimp. |
| 学科主题 | Limnology ; Oceanography |
| 收录类别 | SCI |
| 原文出处 | 10.1007/s00343-012-1195-7 |
| 语种 | 英语 |
| WOS记录号 | WOS:000305906700013 |
| 公开日期 | 2013-09-24 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/12327]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang Dongdong,Li Fuhua,Li Shihao,et al. Expression profiles of antimicrobial peptides (AMPs) and their regulation by Relish[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2012,30(4):611-619. |
| APA | Wang Dongdong,Li Fuhua,Li Shihao,Wen Rong,&Xiang Jianhai.(2012).Expression profiles of antimicrobial peptides (AMPs) and their regulation by Relish.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,30(4),611-619. |
| MLA | Wang Dongdong,et al."Expression profiles of antimicrobial peptides (AMPs) and their regulation by Relish".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 30.4(2012):611-619. |
入库方式： OAI收割
来源：海洋研究所
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