Flounder (Paralichthys olivaceus) FoxD1 and its regulation on the expression of myogenic regulatory factor, MyoD
文献类型：期刊论文
| 作者 | Zhang, Yuqing1,2; Tan, Xungang1 ; Sun, Wei1,2; Zhang, Pei-Jun1
|
| 刊名 | BIOLOGIA
 |
| 出版日期 | 2012-10-01 |
| 卷号 | 67期号:5页码:992-1000 |
| 关键词 | flounder FoxD1 protein over-expression muscle development |
| ISSN号 | 0006-3088 |
| 通讯作者 | Tan, XG (reprint author), Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China. |
| 英文摘要 | It has been reported that FoxD1 plays important roles in formation of several different tissues, such as retina and kidney in vertebrates. The function of FoxD1 in muscle development is, however, unclear although it is expressed in muscle cells in zebrafish. Muscles are the major tissue in fish, which serves as a rich protein source in our diet. To further understand the function of FoxD1 in fish muscle development, here we isolated and characterized the FoxD1 gene from flounder (Paralichthys olivaceus), a valuable sea food and an important fish species in aquaculture in Asia. We analyzed its expression pattern and function in regulating myogenic regulatory factor, MyoD, one of the earliest marker of myogenic commitment. In situ hybridization revealed that FoxD1 was expressed in the tailbud, adaxial cells, posterior intestine, forebrain, midbrain and half of the retina in flounder embryos. Functional studies demonstrated that when flounder FoxD1 was over-expressed in zebrafish by microinjection, MyoD expression was decreased, suggesting that FoxD1 may be involved in myogenesis by regulating the expression of MyoD. |
| 学科主题 | Biology |
| 收录类别 | SCI |
| 原文出处 | 10.2478/s11756-012-0096-8 |
| 语种 | 英语 |
| WOS记录号 | WOS:000307767300022 |
| 公开日期 | 2013-09-24 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/12330]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Yuqing,Tan, Xungang,Sun, Wei,et al. Flounder (Paralichthys olivaceus) FoxD1 and its regulation on the expression of myogenic regulatory factor, MyoD[J]. BIOLOGIA,2012,67(5):992-1000. |
| APA | Zhang, Yuqing,Tan, Xungang,Sun, Wei,&Zhang, Pei-Jun.(2012).Flounder (Paralichthys olivaceus) FoxD1 and its regulation on the expression of myogenic regulatory factor, MyoD.BIOLOGIA,67(5),992-1000. |
| MLA | Zhang, Yuqing,et al."Flounder (Paralichthys olivaceus) FoxD1 and its regulation on the expression of myogenic regulatory factor, MyoD".BIOLOGIA 67.5(2012):992-1000. |
入库方式： OAI收割
来源：海洋研究所
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