Exogenous sodium fumarate enhances astaxanthin accumulation in Haematococcus pluvialis by enhancing the respiratory metabolic pathway
文献类型：期刊论文
| 作者 | Yu, Wenjie1,2,3 ; Zhang, Litao1,2; Zhao, Jing1,2,4; Liu, Jianguo1,2
|
| 刊名 | BIORESOURCE TECHNOLOGY
 |
| 出版日期 | 2021-12-01 |
| 卷号 | 341页码:9 |
| 关键词 | Astaxanthin Haematococcus pluvialis Sodium fumarate Respiratory metabolic pathway Nitrogen deficiency |
| ISSN号 | 0960-8524 |
| DOI | 10.1016/j.biortech.2021.125788 |
| 通讯作者 | Liu, Jianguo(jgliu@qdio.ac.cn) |
| 英文摘要 | Improvement of astaxanthin yield is a continuing objective in Haematococcus pluvialis cultivation. In this study, a new strategy combining exogenous sodium fumarate (SF) with nitrogen deficiency was demonstrated to promote astaxanthin accumulation in H. pluvialis. SF significantly accelerated astaxanthin synthesis over cell growth. Notably, under nitrogen deficiency, 10 mM SF increased the cellular astaxanthin content by 1.75-fold and 1.47 fold on day 7 and 12, respectively. Further studies indicated that SF increased the level of respiratory metabolites in the Embden-Meyerhof-Parnas pathway, tricarboxylic acid cycle and pentose phosphate pathway. An enhanced substrate pool due to the acceleration of respiratory metabolic pathways directly induced astaxanthin synthesis. Meanwhile, the accumulation of C18:1, C18:2 and C18:3 fatty acids enhanced astaxanthin synthesis indirectly by promoting the process of esterification. This study not only helps to elucidate the role of respiratory metabolic pathways in astaxanthin synthesis but also provides a new effective technique to improve astaxanthin production. |
| 资助项目 | National Key Research and Development Program of China[2018YFE0107200] ; National Natural Science Foundation of China[31872588] ; National Natural Science Foundation of China[U1706209] ; Shandong Provincial Natural Science Foundation, China[ZR2019BC057] |
| WOS研究方向 | Agriculture ; Biotechnology & Applied Microbiology ; Energy & Fuels |
| 语种 | 英语 |
| WOS记录号 | WOS:000694798100003 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/176418]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Liu, Jianguo |
| 作者单位 | 1.Chinese Acad Sci, Ctr Ocean Megasci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Qingdao Agr Univ, Sch Marine Sci & Engn, Qingdao 266109, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yu, Wenjie,Zhang, Litao,Zhao, Jing,et al. Exogenous sodium fumarate enhances astaxanthin accumulation in Haematococcus pluvialis by enhancing the respiratory metabolic pathway[J]. BIORESOURCE TECHNOLOGY,2021,341:9. |
| APA | Yu, Wenjie,Zhang, Litao,Zhao, Jing,&Liu, Jianguo.(2021).Exogenous sodium fumarate enhances astaxanthin accumulation in Haematococcus pluvialis by enhancing the respiratory metabolic pathway.BIORESOURCE TECHNOLOGY,341,9. |
| MLA | Yu, Wenjie,et al."Exogenous sodium fumarate enhances astaxanthin accumulation in Haematococcus pluvialis by enhancing the respiratory metabolic pathway".BIORESOURCE TECHNOLOGY 341(2021):9. |
入库方式： OAI收割
来源：海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。