Sesquiterpene and Acetogenin Derivatives from the Marine Red Alga Laurencia okamurai
文献类型：期刊论文
| 作者 | Liang, Yi ; Li, Xiao-Ming; Cui, Chuan-Ming; Li, Chun-Shun; Sun, Hong; Wang, Bin-Gui
|
| 刊名 | MARINE DRUGS
 |
| 出版日期 | 2012-12-01 |
| 卷号 | 10期号:12页码:2817-2825 |
| 关键词 | marine alga Laurencia okamurai bisabolane sesquiterpene C-12-acetogenin brine shrimp lethality |
| ISSN号 | 1660-3397 |
| 通讯作者 | Wang, BG (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China. |
| 英文摘要 | In addition to 13 known compounds, four new bisabolane sesquiterpenes, okamurenes A-D (1-4), a new chamigrane derivative, okamurene E (5), and a new C-12-acetogenin, okamuragenin (6), were isolated from the marine red alga Laurencia okamurai. The structures of these compounds were determined through detailed spectroscopic analyses. Of these, okamurenes A and B (1 and 2) are the first examples of bromobisabolane sesquiterpenes possessing a phenyl moiety among Laurencia-derived sesquiterpenes, while okamuragenin (6) was the first acetogenin aldehyde possessing a C-12-carbon skeleton. Each of the isolated compounds was evaluated for the brine shrimp (Artemia salina) lethal assay and 7-hydroxylaurene displayed potent lethality with LD50 1.8 mu M. |
| 学科主题 | Chemistry, Medicinal |
| 收录类别 | SCI |
| 原文出处 | 10.3390/md10122817 |
| 语种 | 英语 |
| WOS记录号 | WOS:000312607700015 |
| 公开日期 | 2013-09-24 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/12381]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 海洋研究所_胶州湾海洋生态系统国家野外研究站 |
| 作者单位 | Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liang, Yi,Li, Xiao-Ming,Cui, Chuan-Ming,et al. Sesquiterpene and Acetogenin Derivatives from the Marine Red Alga Laurencia okamurai[J]. MARINE DRUGS,2012,10(12):2817-2825. |
| APA | Liang, Yi,Li, Xiao-Ming,Cui, Chuan-Ming,Li, Chun-Shun,Sun, Hong,&Wang, Bin-Gui.(2012).Sesquiterpene and Acetogenin Derivatives from the Marine Red Alga Laurencia okamurai.MARINE DRUGS,10(12),2817-2825. |
| MLA | Liang, Yi,et al."Sesquiterpene and Acetogenin Derivatives from the Marine Red Alga Laurencia okamurai".MARINE DRUGS 10.12(2012):2817-2825. |
入库方式： OAI收割
来源：海洋研究所
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