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The oyster genome reveals stress adaptation and complexity of shell formation
文献类型：期刊论文
| 作者 | Zhang, Guofan2; Fang, Xiaodong1; Guo, Ximing3; Li, Li2; Luo, Ruibang1,4; Xu, Fei2; Yang, Pengcheng1; Zhang, Linlin2; Wang, Xiaotong2; Qi, Haigang2 |
| 刊名 | NATURE
 |
| 出版日期 | 2012-10-04 |
| 卷号 | 490期号:7418页码:49-54 |
| ISSN号 | 0028-0836 |
| 关键词 | TRANSPOSABLE ELEMENTS CRASSOSTREA-GIGAS BIVALVE MOLLUSKS PARAHOX GENES PROTEINS SEQUENCE EVOLUTION DISCOVERY APOPTOSIS PATHWAY |
| 通讯作者 | Wang, J (reprint author), BGI Shenzhen, Shenzhen 518083, Peoples R China. |
| 英文摘要 | The Pacific oyster Crassostrea gigas belongs to one of the most species-rich but genomically poorly explored phyla, the Mollusca. Here we report the sequencing and assembly of the oyster genome using short reads and a fosmid-pooling strategy, along with transcriptomes of development and stress response and the proteome of the shell. The oyster genome is highly polymorphic and rich in repetitive sequences, with some transposable elements still actively shaping variation. Transcriptome studies reveal an extensive set of genes responding to environmental stress. The expansion of genes coding for heat shock protein 70 and inhibitors of apoptosis is probably central to the oyster's adaptation to sessile life in the highly stressful intertidal zone. Our analyses also show that shell formation in molluscs is more complex than currently understood and involves extensive participation of cells and their exosomes. The oyster genome sequence fills a void in our understanding of the Lophotrochozoa. |
| 学科主题 | Multidisciplinary Sciences |
| 收录类别 | SCI |
| 原文出处 | 10.1038/nature11413 |
| 语种 | 英语 |
| WOS记录号 | WOS:000309446800030 |
| 公开日期 | 2013-09-24 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/12252]  |
| 专题 | 海洋研究所_海洋生物技术研发中心 海洋研究所_实验海洋生物学重点实验室 |
| 作者单位 | 1.BGI Shenzhen, Shenzhen 518083, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 3.Rutgers State Univ, Inst Marine & Coastal Sci, Haskin Shellfish Res Lab, Port Norris, NJ 08349 USA 4.HKU BGI Bioinformat Algorithms & Core Technol Res, Hong Kong, Hong Kong, Peoples R China 5.Univ Oxford, Dept Zool, Oxford OX1 3PS, England 6.Clemson Univ, Dept Biol Sci, Clemson, SC 29634 USA 7.Univ So Calif, Dept Biol Sci, Los Angeles, CA 90089 USA 8.Atlantic Cape Community Coll, Mays Landing, NJ 08330 USA 9.Rudjer Boskovic Inst, Lab Evolutionary Genet, HR-10002 Zagreb, Croatia 10.Univ Delaware, Sch Marine Sci & Policy, Lewes, DE 19958 USA |
| 推荐引用方式 GB/T 7714 | Zhang, Guofan,Fang, Xiaodong,Guo, Ximing,et al. The oyster genome reveals stress adaptation and complexity of shell formation[J]. NATURE,2012,490(7418):49-54. |
| APA | Zhang, Guofan.,Fang, Xiaodong.,Guo, Ximing.,Li, Li.,Luo, Ruibang.,...&Wang, Jun.(2012).The oyster genome reveals stress adaptation and complexity of shell formation.NATURE,490(7418),49-54. |
| MLA | Zhang, Guofan,et al."The oyster genome reveals stress adaptation and complexity of shell formation".NATURE 490.7418(2012):49-54. |
入库方式： OAI收割
来源：海洋研究所
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